Follicular helper T (Tfh) cells are a subset of helper T cells with specialised functions to support high-affinity and long-term antibody responses. Tfh cells express high levels of transcription factor Bcl6, chemokine receptor CXCR5, cytokine IL-21 and costimulatory receptor PD-1 and ICOS, ...
t cells follicular helper翻译 T细胞滤泡辅助器(Tfh)是一种负责为B细胞提供帮助的T细胞亚群。它们主要存在于淋巴结和其他淋巴组织中的淋巴滤泡内,从而形成一个高度分化的治愈中心(GC),与B细胞一起产生高亲和力的抗体。由于其对提高免疫应答和维持体内免疫记忆非常重要,因此Tfh细胞已成为外科医生和免疫学家的广泛研究...
Follicular helper T cells (TFH) are able to closely interact with B cells to promote the formation of germinal centers (GCs). The stable cognate interaction between TFH and B cells in the GC is mutually beneficial to both cells for their development and function. Specifically, help B cells ...
Follicular Helper T Cells: 翻译结果5复制译文编辑译文朗读译文返回顶部 Follicular Helper T Cells: 相关内容 ayes i need activity 是我需要活动[translate] adisrases disrases[translate] a悼念那些在地震中遇难的人们 Mourns these the people who died in the earthquake[translate] ...
Although T cell help for B cells was described several decades ago, it was the identification of CXCR5 expression by B follicular helper T (Tfh) cells and the subsequent discovery of their dependence on BCL6 that led to the recognition of Tfh cells as an independent helper subset and accelera...
Follicular helper T (Tfh) cells provide help to B cells and allow formation of long-livedantibody responses. Despite an improved understanding of the molecular program that drives Tfh cell formation, their definition remains elusive: neither follicular homing ability, Bcl-6 expression nor IL-21 secr...
Immunization leads to the formation of germinal centres (GCs) that contain both T follicular helper (Tfh) and T follicular regulatory (Tfr) cells. Whether T-cell receptor (TCR) specificity defines the differential functions of Tfh and Tfr cells is unclea
The aim of this study was to investigate the possible role of follicular helper T (TFH) cells in the pathogenesis of primary Sjögren's syndrome (pSS) by analyzing immune-competent cells and serological markers with special emphasis on clinical symptoms. We enrolled 50 pSS patients and 16 heal...
T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and vaccinations. However, if they get out of control, this can cause diseases such as autoimmunity, allergies or cancer.
follicular helper T (Tfh) cells are recruited to the liver to upregulate hepatic granuloma formation and liver injury inS. japonicum-infected mice, and identified a novel function of macrophages in Tfh cell induction. In addition, our results showed that the generation of Tfh cells driven by ...