National Academy of SciencesProceedings of the National Academy of Sciences of the United States of AmericaToptan T, Abere B, Nalesnik M A, et al. Circular DNA tumor viruses make circular RNAs. Proc Natl Acad Sci USA, 2018, 115(37): E8737-E8745...
Circular DNA tumor viruses make circular RNAs Proc. Natl. Acad. Sci. U.S.A., 115 (37) (2018), pp. E8737-e8745, 10.1073/pnas.1811728115 View in ScopusGoogle Scholar Ungerleider et al., 2018 N. Ungerleider, et al. The Epstein Barr virus circRNAome PLoS Pathog., 14 (8) (2018), ...
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CircRNAs are a class of single-stranded RNAs with covalently linked head-to-tail topology. In the decades since its initial discovery, their biogenesis, regulation, and function have rapidly disclosed, permitting a better understanding and adoption of th
An independent second “active” model describes the relationship between linear splicing and backsplicing by focusing on the question whether circRNAs (as single-stranded RNAs) can hybridize with DNA in cells (Fig.2b). Indeed circRNAs are complementary to the template DNA strand from which they de...
Circular RNAs (CircRNAs) are single-stranded, covalently closed RNA molecules that are ubiquitous across species ranging from viruses to mammals. Important advances have been made in the biogenesis, regulation, localization, degradation and modification of circRNAs. CircRNAs exert biological functions by ...
64. Yang WT, Zheng PS. Promoter hypermethylation of KLF4 inactivates its tumor suppressor function in cervical carcinogenesis. PLoS One. 2014;9:e88827 65. Hou LD, Zhang J. Circular RNAs: An emerging type of RNA in cancer. Int J Immunopathol Pharmacol. 2017;30:1-6 ...
extrachromosomal DNA elements of diverse sizes and numbers were observed in mitotic human tumor cells. They were referred to as double minutes (DMs) at that time, as they usually appear in pairs.34,35Since then, researchers have focused on updating the understanding of these extrachromosomal partic...
Circular DNA tumor viruses make circular RNAs Proc. Natl. Acad. Sci. USA, 115 (2018), pp. E8737-E8745 View in ScopusGoogle Scholar Wang et al., 2014 X. Wang, Z. Lu, A. Gomez, G.C. Hon, Y. Yue, D. Han, Y. Fu, M. Parisien, Q. Dai, G. Jia, et al. N6-methyladenosine...