Chronic White Matter Degeneration, but No Tau Pathology at One-Year Post-Repetitive Mild Traumatic Brain Injury in a Tau Transgenic Model.doi:10.1089/neu.2018.5720Benoit Christian MouzonCorbin BachmeierJoseph OjoChristopher AckerScott FergusonGogce Crynen...
We investigated associations between DTI indices of three brainstem white matter tracts, traumatic brain injury (TBI) injury characteristics, and postconcussive symptomatology (PCS) in a well-characterized sample of veterans with history of mild to moderate TBI (mTBI). 58 military veterans (mTBI: n...
Chronic cerebral hypoperfusion leads to white matter injury (WMI), which subsequently causes neurodegeneration and even cognitive impairment. However, due
1A–C). The meshes consisted of eight tissue types, namely brain white matter (WM), brain grey matter (GM), cerebro-spinal fluid (CSF), compact bone of the skull, spongy bone, the vitreous bodies of the eyes, the surrounding eye regions and skin. In addition, the paranasal sinuses ...
Background: Vascular cognitive impairment and dementia (VCID) is the second most common form of dementia after Alzheimer's disease (AD). Currently, the mechanistic insights into the evolution and progression of VCID are not fully understood. White matter change represents an invariant feature of ...
Introduction Traumatic brain injury (TBI) is a recognized risk factor for later development of neurodegenerative disease. However, themechanisms contributing to neurodegeneration following TBI remain obscure. In this study, we examined the chronic neurobehavioral and neuropathological outcomes following single...
We aimed to evaluate whether white and gray matter microstructure changes observed with magnetic resonance imaging (MRI)-based diffusion tensor imaging (DTI) can be used to reflect the progression of chronic brain trauma. The MRI-DTI parameters, neuropat
Blood-brain barrier dysfunction in Binswanger’s disease; an immunohistochemical study Binswanger’s disease is pathologically characterized by a combination of diffuse cerebrovascular white matter lesions and lacunar infarcts in the basal ga... I. Akiguchi,Hidekazu Tomimoto,Toshihiko Suenaga,... - 《...
& White, S. R. Brain charts for the human lifespan. Nature. 604, 525–533 (2022). Article PubMed PubMed Central Google Scholar Mathys, H. et al. Single-cell transcriptomic analysis of Alzheimer’s disease. Nature 570, 332–337 (2019). Article PubMed PubMed Central Google Scholar ...
Strongest GVL occurs when the transplantation is performed during the chronic phase in the presence of minimal residual disease, detectable by molecular testing. Weakest GVL effect occurs when the transplantation is performed in a blastic phase and/or T-cell depletion is used for prevention ...