Chronic myeloid leukemia (CML) is caused byBCRABL1in a cell with the biological potential, intrinsic or acquired, to cause leukemia. This cell is commonly termed the CML leukemia stem cell (LSC). In humans a CML LSC is operationally-defined by ≥1 in vitro or in vivo assays of human leu...
Chronic myeloid leukemia (CML) is caused byin a cell with the biological potential, intrinsic or acquired, to cause leukemia. This cell is commonly termed the CML leukemia stem cell (LSC). In humans a CML LSC is operationally-defined by 鈮 1 in vitro or in vivo assays of human leukemia...
慢性粒细胞白血病(Chronic myeloid leukemia,CML),是一种起源于骨髓造血细胞并侵入血液的癌症。成人白血病中约15%是慢性粒细胞白血病。酪氨酸激酶抑制剂(TKI)有助于改变疾病的预后,与其他癌症治疗相比,副作用更少。然而,TKI只控制了疾病的发展,留下了产生耐药性的可能性。值得庆幸的是,来自广岛大学的研究人员报告说,...
chronic myeloid leukemia 美 英 un.慢性粒细胞性白血病 英汉 un. 1. 慢性粒细胞性白血病
Targeting DDX3X eliminates leukemia stem cells in chronic myeloid leukemia by blocking NT5DC2 mRNA translation Chen Duan Xiaoying Lin Yanli Jin Research08 Nov 2024 Oncogene P: 1-14 The BIM deletion polymorphism potentiates the survival of leukemia stem and progenitor cells and impairs response to...
Chronic Myeloid Leukemia is a type of cancer characterized by the presence of immature myeloid cells in the skin and subcutaneous tissue, which can be identified through positive staining with specific markers. From: Modern Surgical Pathology (Second Edition), 2009 ...
CML is a cancer of the bone marrow and white blood cells. It is a form of leukemia that is characterised by an increased growth of myeloid cells in the bone marrow and the accumulation of these cells in the blood. Like many cancers, CML m...
Myeloid leukemias, including acute myeloid leukemia (AML) and chronic myeloid leukemia (CML), are clonal bone marrow diseases characterized by the pathological proliferation of abnormal white blood cells. A large number of studies have addressed myeloid leukemia classification, diagnosis, pathogenesis and...
variants also chronic myeloid leukemia or chronic myelocytic leukemia : myelogenous leukemia that is marked by an abnormal increase in mature and immature granulocytes (as neutrophils, eosinophils, and myelocytes) especially in bone marrow and blood, that is characterized by fatigue, weakness, loss of...
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