Oligovascular coupling contributes to white matter vascular homeostasis. However, little is known about the effects of oligovascular interaction on oligodendrocyte precursor cell (OPC) changes in chronic cerebral ischemia. Here, using a mouse of bilatera
Relationship between aortic stiffening and microvascular disease in brain and kidney: cause and logic of therapy. Hypertension. 2005;46(1):200–4. Article PubMed Google Scholar Jankowski J, Floege J, Fliser D, Bohm M, Marx N. Cardiovascular Disease in chronic kidney disease: pathophysiological...
<bold>Objective</bold> To analyze the correlation between the changes of learning and memory and the progressive degeneration of white matter nerve fibers and pericytes in the corpus callosum and hippocampus of rats with chronic cerebral ischemia, then t
Clinically, extensive injury from ischemic stroke results from ischemia-reperfusion (IR), which is accompanied by inflammation, blood-brain barrier (BBB) damage, neural cell death, and extensive tissue loss. Tissue plasminogen activator (tPA) is still the only US Food and Drug Administration–...
MRI Visualization of Whole Brain Macro- and Microvascular Remodeling in a Rat Model of Ischemic Stroke: a Pilot Study. Sci Rep. 2020;10:4989. (Open in a new window)PubMed (Open in a new window)Web of Science ®(Open in a new window)Google Scholar...
Objectives To assess the longitudinal changes of microvascular function in different myocardial regions after myocardial infarction (MI) using myocardial blood flow derived by dynamic CT perfusion (CTP-MBF), and compare CTP-MBF with the results of cardiac magnetic resonance (CMR) and histopathology.Meth...
However, in contrast to ischemia, in EAE, SUR1 expression was found to be minimal or absent in microvascular endothelium, whereas it was very prominent in perivascular structures consistent with astrocytes and astrocytic foot processes (Fig. 7h)....
The CKD cohort showed significant vascular fibrosis, collagen deposition, microvascular rarefaction, and tubulointerstitial abnormalities in the kidneys compared to the control. Induction of transient focal ischemia (by MCA occlusion) on day 28 of adenine treatment led to bigger infarcts (estimated by ...
Chapter 5 Coronary Microvascular Dysfunction Chapter 6 Precipitants Of Myocardial Ischemia Part III. Clinical Evaluation Chapter 7 History And Physical Examination Chapter 8 Lipid Measurements Chapter 9 Standard And Novel Biomarkers Chapter 10 Ecg And Standard Exercise Stress Testing ...
(Fig.1). Neuronal-capillary interactions at the BBB involve the endothelial cells, basal lamina, astrocyte foot processes, and pericytes. Tight junctions between the endothelial cells serve to restrict the passage of solutes. The BBB is susceptible to changes in blood-flow, ischemia, and ...