Before induced pluripotent stem cells (iPSCs) can be used to treat neurologic diseases, human iPSC-derived neural cells must be analyzed in the primate brain. In fact, although mouse and human iPSCs have been used to generate dopaminergic (DA) neurons that are beneficial in rat models of ...
Chronic electrical stimulation of the contralesional lateral cerebellar nucleus enhances recovery of motor function after cerebral ischemia in rats. Brain Res. 1280, 107–116 (2009). Article CAS PubMed PubMed Central Google Scholar Machado, A. G. et al. Chronic 30-Hz deep cerebellar stimulation...
Oligovascular coupling contributes to white matter vascular homeostasis. However, little is known about the effects of oligovascular interaction on oligodendrocyte precursor cell (OPC) changes in chronic cerebral ischemia. Here, using a mouse of bilatera
摘要: PurposeTo determine whether the perfusion deficit could predict brain infarction in patients with chronic cerebral ischemia who experienced recurring episodes of neurological symptoms and showed a perfusion-diffusion mismatch on magnetic resonance (MR) images....
meningitis- infectious disease characterized by inflammation of the meninges (the tissues that surround the brain or spinal cord) usually caused by a bacterial infection; symptoms include headache and stiff neck and fever and nausea choriomeningitis- a cerebral meningitis with cellular infiltration of the...
V. I. Skvortsov, “Ischemic stroke: pathogenesis, ischemia, therapeutic approaches,” Nevrol. Zh., 3, 4–10 (2001). V. L. Feigin, Yu. P. Nikitin, and V. A. Kholodov, “Epidemiology of cerebral stroke in Siberia from registry data,” in: Epidemiology and the Organization of Neurologi...
Clinically, extensive injury from ischemic stroke results from ischemia-reperfusion (IR), which is accompanied by inflammation, blood-brain barrier (BBB) damage, neural cell death, and extensive tissue loss. Tissue plasminogen activator (tPA) is still the only US Food and Drug Administration–...
Schmidt-Kastner RFreund TF Selective vulnerability of the hippocampus in brain ischemia. Neuroscience 1991;40599- 636PubMedGoogle ScholarCrossref 57. Fujioka MOkuchi KHiramatsu KISakaki TSakaguchi SIshii Y Stroke. Stroke 1997;28584- 587PubMedGoogle ScholarCrossref 58. Katz HDavies CDobbing J ...
AIM: To observe the influence of mongolian milkvetch root injection on the cognitive disorder of patients with chronic cerebral ischemia and provide research evidences for this injection's further application in clinic. METHODS: The experiment was carried out among 86 outpatients or inpatients from Ger...
A variety of drug delivery vehicles have been established for the targeted and controlled delivery of therapeutic agents in a wide range of chronic diseases, such as diabetes, cancer, atherosclerosis, myocardial ischemia, asthma, pulmonary tuberculosis, Parkinson’s disease, and Alzheimer’s disease. ...