This wealth of information coupled to the ease of genetic screening in nematodes has started to shed light on the mechanisms of genome folding inside the nuclear space. Worms have provided more than a mere description of the three-dimensional configuration of the genome, helped uncover functional ...
DNA in the nucleus is packed into chromatin using proteins.Mitosis requires that the cell's chromatin be further packed into specific structures that are called chromosome which from a unique karyotype for each species.During mitosis the parent cell DNA is separated such that each daughter cell rec...
Immuno-staining revealed these marks were not homogeneously distributed in the nucleus, indicating distinct euchromatin and heterochromatin compartments in tomato: euchromatin occurred in the centre of the nucleus while constitutive heterochromatin occurred at the nuclear periphery (Fig. 1a, Supplementary Fig...
model emerged, in which sub-nucleolar domains represent individual stages of the unidirectional process of ribosome biogenesis: The synthesis of rRNA takes place at the fibrillar center (FC) - dense fibrillar component (DFC) border, while early and late steps of ribosome maturation occur in the DF...
Thus, the chromatin in the nucleus may not be directly accessible to transcription factors. The structure of chromatin affects DNA replication. For example, the euchromatin and other active areas of the genome replicate earlier. Similarly, in the heterochromatin and silent area around it, the ...
Chromosome architecture in the decondensing human sperm nucleus Whereas recent studies demonstrated a well-defined nuclear architecture in human sperm nuclei, little is known about the mode of DNA compaction above the e... M Olga,T Nikolai,Z Andrei 被引量: 0发表: 2018年 Differential chromosomal ...
The chromatin structure of DNA determines genome compaction and activity in the nucleus. On the basis of in vitro structures and electron microscopy (EM) studies, the hierarchical model is that 11-nanometer DNA-nucleosome polymers fold into 30- and subsequently into 120- and 300- to 700-nanomete...
It is increasingly clear that the packaging of DNA in nucleosome arrays serves not only to constrain the genome within the nucleus, but also to encode information concerning the activity state of the gene. Packaging limits the accessibility of many regulatory DNA sequence elements and is functionally...
Chromatin in which of the following states is the most euchromatic?? in a sperm nucleusin a transcribed gene during G1;in a Barr body;in a silenced gene during M phas 相关知识点: 试题来源: 解析 in a transcribed gene during G1;
The first stage of cell division. Before prophase begins, the chromosomes duplicate to form two long, thin strands called chromatids. During prophase itself, the chromatids condense and thicken and the membrane surrounding the nucleus disappears. In mitosis, prophase is followed by metaphase. See ...