Biology definition: Chromatin is a substance made up of DNA or RNA and proteins, such as histones. It condenses during cell division (mitosis or meiosis) and becomes a chromosome. Chromatins are“unwound” condensed structures whereas chromosomes are highly packaged and more condensed than chroma...
Kyle has taught college level biology and helped with middle-school science programs. Have you ever wondered how or why the cells of our body store information? Many of us know that the molecule DNA contains all the information that makes us who we are. After this lesson you will be able...
Define Chromatin condensation. Chromatin condensation synonyms, Chromatin condensation pronunciation, Chromatin condensation translation, English dictionary definition of Chromatin condensation. n. 1. The first stage of mitosis, during which the chromoso
AI generated definition based on:Brenner's Encyclopedia of Genetics (Second Edition),2013 About this page Add to MendeleySet alert Also in subject areas: Biochemistry, Genetics and Molecular Biology Immunology and Microbiology Medicine and Dentistry ...
Anuja A.George, ...Gordon L.Hager, inThe International Journal of Biochemistry & Cell Biology, 2009 In an analysis of theGRresponse element, it was reported that activation of GR led to the recruitment ofhepatocyte nuclear factor5 wherein it appears that GR initiates the nucleosome transition ...
nature structural & molecular biology articles articleArticle Open access Published: 22 December 2022 Diverse silent chromatin states modulate genome compartmentalization and loop extrusion barriers George Spracklin, Nezar Abdennur, Maxim Imakaev, Neil Chowdhury, Sriharsa Pradhan, Leonid A. ...
(ABC) model was recently developed to predict enhancer-target gene pairs in a given cell type under the premise that the extent to which an element regulates a gene’s expression depends on its strength as an enhancer (activity level), scaled by how often it is near that gene’s promoter...
At the single-cell level, most single cells also exhibited a reverse correlation between chromatin interactions and genomic distance, whereas a minority of single cells exhibited the highest chromatin interactions and not necessarily at the lowest genomic distances, a deviation from the aggregatePc–sre...
Due to the integration of HPV at varying genomic regions, these analyses compared one sample to a population and therefore suffer from a lack of statistical power. We compensated for such limitations by using a restrictive definition for considering outlier genes and visualizing raw signal and ...
In recent work from Cavalli and colleagues, super resolution microscopy enabled definition of significantly decreased intra-TAD chromatin interactions in the absence of cohesin complexes [61]. Thus, results from bulk cell chromatin sequencing and single cell super resolution microscopy each suggest roles ...