Chou-Talalay methodSynergyTriple Negative Breast Cancer (TNBC) treatment is more challenging than other subtypes of breast malignancy and due to the lack of markers for the molecularly targeted therapies (ER, PR, and HER-2/Neu), the conventional chemotherapeutic agents are still the mainstay of ...
图 1 Chou-Talalay 的数学模型 Fig 1 A mathematical model of Chou-Talalay method 1.2 Chou-Talalay 结果分析 在确定药物数目,有无竞争作用以及剂量配 比的条件下,通过对 MTT 获得的量-效关系数据进 行等量效比较和等效量比较处理而对药物联合作 用进行定性及定量描述."CompuSyn"软件根据 Chou-Talalay 建立的...
Chou-Talalay药物联用研究的统计方法 关于药物联用的定量研究 T A N K西安天工生物医药研究所
agreement yet,especially the synergistic effect of drug combination.Chou-Talalay method is now generally accepted as synergy quantitative analysis method for drug combination.Aiming at the anti-tumor research field,we comprehensively reviewed the method to lay a good basis for the rational use of ...
Chou-Talalay 在抗肿瘤联合用药中的研究应用概况.PDF,[24] WU S, XING D. Mechanism of mitochondrial membrane M, et al. Cytotoxicity of PP(Arg)(2)- and Hp(Arg)(2)-mediated permeabilization during apoptosis under photofrin-mediated photodynamic therapy and ear
Drug combination studies and their synergy quantification using the Chou-Talalay method. This brief perspective article focuses on the most common errors
Sample TextSample Text 最近需要用 Combination Index （Chou-Talalay Method）计算两药（多药）联用的...
A checkerboard method to evaluate interactions between drugs to diagnose the interaction between agents and obviate the need to test their mixtures in a fixed concentration ratio as proposed by Chou and Talalay. Dos... JJ Martinez-Irujo,ML Villahermosa,E Alberdi,... - 《Biochemical Pharmacology》...
KEY WORDS: Chou-Talalay method; anti-tumor; drug combination; quantitative analysis 肿瘤是导致人类死亡的一个主要原因。 世界卫生组织 2010 年肿瘤患者死亡率调查报告显示, 全球每年有 760 多万人被肿瘤夺去生命。 根据近年文献报道, 对于长期给予单一药物治疗的肿瘤患作者简介: 王士群, 男, 硕士生 Tel: (...
Chou-Talalay method is now generally accepted as synergy quantitative analysis method for drug combination. Aiming at the anti-tumor research field, we comprehensively reviewed the method to lay a good basis for the rational use of drugs. Keywords: Chou-Talalay method / anti-tumor / drug ...