Chou-Talalay药物联用研究的统计方法 关于药物联用的定量研究 T A N K西安天工生物医药研究所
Combination index calculation using Chou and Talalay method in PEL cell lines.Azhar, R. HussainSaeeda, O. AhmedMaqbool, AhmedOmar, S. KhanSally, Al AbdulMohsenLeonidas, C. PlataniasKhawla, S. AlKurayaShahab, Uddin
Chou-Talalay( 又称中位药效法 , median-drug effect analysis;联合指数法,combination index method)是由 Chou 和 Talalay 于 1984 年共同建立的 药物联合作用的定量方法.于 2005 年,由 Martin 等[4]组成的团队针对 Chou-Talalay 的数学模型开 发出第 3 代药物联合作用量-效分析软件 "CompuSyn",使得该法的...
Chou-Talalay 在抗肿瘤联合用药中的研究应用概况.PDF,[24] WU S, XING D. Mechanism of mitochondrial membrane M, et al. Cytotoxicity of PP(Arg)(2)- and Hp(Arg)(2)-mediated permeabilization during apoptosis under photofrin-mediated photodynamic therapy and ear
KEY WORDS: Chou-Talalay method; anti-tumor; drug combination; quantitative analysis 肿瘤是导致人类死亡的一个主要原因。 世界卫生组织 2010 年肿瘤患者死亡率调查报告显示, 全球每年有 760 多万人被肿瘤夺去生命。 根据近年文献报道, 对于长期给予单一药物治疗的肿瘤患作者简介: 王士群, 男, 硕士生 Tel: (...
Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method This brief perspective article focuses on the most common errors and pitfalls, as well as the do9s and don9ts in drug combination studies, in terms of expe... TC Chou - 《Cancer Research》 被引量: 2869...
Sample TextSample Text 最近需要用 Combination Index （Chou-Talalay Method）计算两药（多药）联用的...
Drug combination studies and their synergy quantification using the Chou-Talalay method. This brief perspective article focuses on the most common errors
Chou-Talalay methodSynergyTriple Negative Breast Cancer (TNBC) treatment is more challenging than other subtypes of breast malignancy and due to the lack of markers for the molecularly targeted therapies (ER, PR, and HER-2/Neu), the conventional chemotherapeutic agents are still the mainstay of ...
Chou-Talalay method is now generally accepted as synergy quantitative analysis method for drug combination. Aiming at the anti-tumor research field, we comprehensively reviewed the method to lay a good basis for the rational use of drugs. Keywords: Chou-Talalay method / anti-tumor / drug ...