Cholesterol 7α-hydroxylase (CYP7A): patterns of messenger RNA expression during rat liver development. Hepatology. 1998; 28 :1064–1072.Massimi M, Lear SR, Huling SL, Jones AL, Erickson SK (1998) Cholesterol 7alpha-hydroxylase (CYP7A): patterns of messenger RNA expression during rat liver ...
Rat liver cholesterol 7 alphahydroxylase. Pretranslational regulation for circadian rhythm - NOSHIRO, NISHIMOTO, et al. - 1990 () Citation Context ...iurnal expression of Cyp7a1. Cyp7a1 mRNA, protein, and enzyme activity are maximal in nonlactating rodents during the dark cycle when food ...
目的探讨胆固醇7α-羟化酶(cholesterol 7α-hydroxylase,CYP7A1)基因多态性与阿尔茨海默病(AD)的关系。 更多例句>> 3) CYP7A1 胆固醇-7α羟化酶 4) Cholesterol 7α-hydroxylase 胆固醇7α羟化酶 例句>> 5) CYP7A1 gene 胆固醇7α-羟化酶基因 ...
Cholesterol 7alpha-hydroxylase (CYP7A): patterns of messenger RNA expression during rat liver development. Cholesterol 7 alpha-MonooxygenaseGene Expression Regulation, Developmental胆固醇7α单加氧酶基因表达调控, 发育期肝转录, 遗传Cholesterol 7α-hydroxylase is a ... M, Massimi,SR Lear,SL Huling,.....
Objective To study the association ofcholesterol 7α-hydroxylase(CYP7A1) gene polymorphism with Alzheimer\'s disease(AD). 目的探讨胆固醇7α-羟化酶(cholesterol 7α-hydroxylase,CYP7A1)基因多态性与阿尔茨海默病(AD)的关系。 更多例句>> 4) CYP7A1 ...
The establishement of the circadian rhythm of cholesterol 7α-hydroxylase activity requires protein and RNA synthesis. The spontaneous decrease of the enzymic activity, at the end of the night, allows us to evaluate a half-life time of about two hours. The half-life time goes up to about fou...
The objective of this study is to elucidate the mechanism of insulin regulation of cholesterol 7α-hydroxylase gene expression in human hepatocytes. Real-time PCR assays showed that physiological concentrations of insulin rapidly stimulated cholesterol 7α-hydroxylase (CYP7A1) mRNA expression in primary...
7alpha-hydroxylase (CYP7A1), the key regulatory gene in bile acid synthesis. Activation of an AMP-activated protein kinase (AMPK) decreased CYP7A1 mRNA, hepatocyte nuclear factor 4alpha (HNF4alpha) protein, and binding to CYP7A1 chromatin. Glucose increased ATP levels to inhibit AMPK and ...
A human cholesterol 7α-hydroxylase gene spanning 17 kb in length which includes the sequence 5′ flanking region (6. kb) and that of the entire transcriptional region (10.5 kb) was obtained from two partially overlapping clones (i.e., HG 18 and HG 17) of a human genomic library. The ...
We demonstrated that APOBEC-1 binds to AU-rich regions of the 3'-untranslated region of the Cyp7a1 transcript, containing the UUUN(A/U)U consensus motif, using both UV cross-linking to recombinant APOBEC-1 and in vivo RNA co-immunoprecipitation. In vivo Apobec-1-dependent modulation of ...