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Cholesterol 7α-hydroxylase (CYP7A): patterns of messenger RNA expression during rat liver development. Hepatology. 1998; 28 :1064–1072.Massimi M, Lear SR, Huling SL, Jones AL, Erickson SK (1998) Cholesterol 7alpha-hydroxylase (CYP7A): patterns of messenger RNA expression during rat liver ...
摘要: A method for controlling cholesterol is provided. A cholesterol 7-alpha-hydroxylase (C7&agr;H) regulatory factor is administered to control cholesterol catabolism. Also provided is a method for producing the cholesterol control agent and a nucleotide sequence involved in regulatory control.收藏...
Bile acid synthesis plays a critical role in the maintenance of mammalian cholesterol homeostasis. The CYP7A1 gene encodes the enzyme cholesterol 7alpha-hydroxylase, which catalyzes the initial step in cholesterol catabolism and bile acid synthesis. We report here a new metabolic disorder presenting ...
Cholesterol 7 Alpha-Hydroxylase 作者:Surhone, Lambert M.; Tennoe, Mariam T.; Henssonow, Susan F. 页数:76 ISBN:9786135496666 豆瓣评分 目前无人评价 评价: 写笔记 写书评 加入购书单 分享到 推荐
A good correlation of the levels of mRNA to the enzyme activities and the protein levels demonstrates that pretranslational regulation is most likely a mechanism for the circadian rhythm of 7 alpha-hydroxylase. The marked diurnal fluctuation of the amount of protein and the level of mRNA also ...
Cholesterol 7-alpha hydroxylase DAB: Diaminobenzidine DEG: Differentially expressed genes Dio3os: Dio3 antisense RNA DNMT: DNA methyltransferases ECL: Enhanced chemiluminescence ESR1: Estrogen receptor 1 ESRRA: Estrogen-related receptor alpha FBS: Fetal bovine serum FOSL2: FOS like 2, AP...
Cholesterol 7 alpha-hydroxylase, the cytochrome P-450-dependent and rate-controlling enzyme of bile acid synthesis, was purified from rat and human liver microsomes. The purified fractions were assayed in a reconstituted system containing [4-14C]cholesterol, and cholesterol 7 alpha-hydroxylase activitie...
Cholesterol 7-alpha-HydroxylaseOrgan SizeHepatectomyHepatic is a rate-limiting enzyme for , and we have previously shown that the serum 7 alpha-hydroxycholesterol level reflects the in patients with an intact liver. The purpose of this study was to evaluate the alterations in hepatic activity and ...
The regulation of cholesterol 7 alpha-hydroxylase activity by estradiol and progesterone was investigated in liver microsomes isolated from rats fed standard diet, either ad libitum or fasted for 24 h, and diet containing the bile acid sequesterant cholestyramine. Differential effects were observed when...