OBJECTIVES: Advanced-stage (Child-Pugh classes B and C) liver cirrhosis (LC) is a contraindication for oesophagectomy. However, the question as to whether Child-Pugh class A LC may have an impact on perioperative outcomes remains unanswered. This retrospective single-centre study was designed to...
上述研究成果以“ImmuneCheckpointInhibitorsforChild-PughClassBAdvancedHepatocellularCarcinoma:ASystematicReviewandMeta-Analysis”为题在美国医学会肿瘤学期刊《JAMAOncology》发表交大二附院为第一作者和通讯作者单位,内科学传染病专业博士生谢恩睿为第一作者,杨毅辉博士和BernhardScheiner博士为共同第一作者;感染科纪泛扑为末...
研究数据支持部分Child-Pugh B级的晚期HCC可获益于ICIs免疫治疗,但仍需要更多的研究来确定这一人群中哪些人更能获益于ICIs治疗。 摘译自:Xie E, Yeo YH, Scheiner B, et al. Immune Checkpoint Inhibitors for Child-Pugh Class B Advanced Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis. JAMA ...
洛杉矶Cedars-Sinai Medical Center杨毅辉和Ju Dong Yang博士团队、伦敦Imperial College London,David J. Pinato教授团队合作在JAMA Oncology发表“Immune Checkpoint Inhibitors for Child-Pugh Class B Advanced Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis”(图1)。
总体而言,该项研究结果表明:Child-Pugh B级晚期HCC患者使用ICIs治疗尽管总体疗效低于Child-Pugh A 级的患者,但有相当一部分患者获得肿瘤应答,且安全性与Child-Pugh A 级患者无差别。研究数据支持部分Child-Pugh B级的晚期HCC可获益于ICIs免疫治疗,但仍需要更多的研究来确定这一人群中哪些人更能获益于ICIs治疗。
In this study, we examine the outcome of hepatic resection for HCC within the Milan criteria, and determine the effectiveness of hepatic resection as the primary treatment for HCC within the Milan criteria in Child-Pugh class A. Methods: 110 patients underwent curative surgical resection for HCC ...
一般不说patients with Child-Pugh (class) C,而是patients with Child-Pugh (class) C cirrhosis或者Child-Pugh (class) C patients;总之,Child-Pugh (class) C在这里相当于定语。 在英文中如果要表达“客观反映了……”,这个“客观”一般可以考虑译成accurately,而不是objectively(有很重的中式英语味道)。编辑...
Class A represents mild liver dysfunction, while class C indicates severe liver dysfunction with a poor prognosis. Child-Pugh分级根据五个参数得分将患者分为三个等级- A级、B级和C级。A级表示轻度肝功能障碍,而C级表示肝功能重度障碍且预后不佳。 In addition to evaluating liver function, the Child-Pugh...
Objective To analyse the outcomes of patients with Child-Pugh A class cirrhosis and a single hepatocellular carcinoma(HCC) up to 5 cm in diameter who underwent liver transplantation versus resection. Methods During 2007 to 2011, 263 Child-Pugh A class cirrhotic patients with a single HCC up to...
2.1肝硬化患者的Child-pugh评分结果 本组76例肝硬化患者,根据Child-pugh评分标准进行分级,其中肝硬化A级33例,肝硬化B级26级,肝硬化C级17例。 2.2不同Child-pugh分级肝硬化患者血清PA的差异 Child-Pugh A组血清PA值明显低于正常对照组,差异具有统计学意义(t=3.878,P<0.01);Child-Pugh B组血清PA值明显低于正常对...