incubate tumor cells with gold nanorods linked to CpG before exposing them to UV light to create apoptotic bodies laden with gold nanorods. The photothermal action induced by gold nanorods under NIR light irradiation successfully kills the tumor.41 PA is a nano-drug that is used to treat cancer...
cell-based systems, such as erythrocytes31,32, platelets, stem cells, monocytes/macrophages, lymphocytes, dendritic cells, neutrophils, have emerged as interesting alternatives to biological drug carriers33. These cell systems possess numerous advantages...
Fig. 7a shows the mechanism of the Ti3C2-CoNWs nanocarrier heterojunction efficiently enter the cancer cells by endocytosis [52] and then kills the cancer cells upon NIR irradiation by chemo-photothermal therapy. Primarily, it is well-known that the safety and toxicity of nanocarriers are major ...
Furthermore, in radiation therapy, the therapeutic ratio is the maximum radiation dose that kills cancer cells locally. A low acute and late morbidity is associated with the minimum radiation dose in normal tissues [63]. Single-cell ionization is used to determine how much energy is required to...
A subset of new platinum antitumor agents kills cells by a multimodal mechanism of action also involving changes in the organization of the microtubule cytoskeleton. J. Med. Chem. 2019, 62, 5176–5190. [Google Scholar] [CrossRef] [PubMed] Macias, F.J.; Deo, K.M.; Pages, B.J.; ...
[71] reported that curcumin was able to shut down the pathways of MCF7 and SUM159 sphere-forming cells. The study revealed that the phytochemical kills BCSCs because of the downregulation of the two pathways [71]. Resveratrol, a polyphenolic compound found in cranberries, peanuts, and ...
This effect appears to be general, as ATMi kills tumor cells treated with cognate TKIs targeting different activated oncogenes (EGFR, ALK, KRAS, and BRAF) in different tumor types (lung, pancreatic, melanoma, and acute myeloid leukemia). Interestingly, TKI + ATMi is cytotoxic even in cells ...
After phototherapy rapidly and efficiently kills tumor cells, chemotherapy can eliminate the residual tumor cells for a long time. Therefore, chemo–phototherapy can significantly improve the treatment efficiency. Nowadays, physical therapies such as ultrasound therapy and magnetic hyperthermia are also ...
Patients with cancer have multiple treatment options available to them today, but each has its drawbacks. Chemotherapy kills rapidly dividing cancer cells, but it also damages healthy cells in the body and often does not effectively prevent tumor metasta