but each has its drawbacks. Chemotherapy kills rapidly dividing cancer cells, but it also damages healthy cells in the body and often does not effectively prevent tumor metastasis or disease recurrence. Immunotherapies avoid those problems by acting on a patient's immune system to generate a sustain...
T cells are the part of the immune system that kills infected cells. In CAR-T, they're altered to recognize and attack cells with selected proteins on their surfaces. Certain types of leukemia and lymphoma are relatively easy targets for CAR-T, because the type of white blood cell that ha...
incubate tumor cells with gold nanorods linked to CpG before exposing them to UV light to create apoptotic bodies laden with gold nanorods. The photothermal action induced by gold nanorods under NIR light irradiation successfully kills the tumor.41 PA is a nano-drug that is used to treat cancer...
Fig. 7a shows the mechanism of the Ti3C2-CoNWs nanocarrier heterojunction efficiently enter the cancer cells by endocytosis [52] and then kills the cancer cells upon NIR irradiation by chemo-photothermal therapy. Primarily, it is well-known that the safety and toxicity of nanocarriers are major ...
T cells are the part of the immune system that kills infected cells. In CAR-T, they're altered to recognize and attack cells with selected proteins on their surfaces. Certain types of leukemia and lymphoma are relatively easy targets for CAR-T, because the type of white blood cell that ha...
In radiation therapy (RT), high-energy radiation destroys the cancer cells’ reproduction ability, and the body naturally removes these cells. Such high-energy radiation may cause inadvertent damage to the healthy cells surrounding the tumor. Combining radiation and chemotherapies improves therapeutic ef...
A subset of new platinum antitumor agents kills cells by a multimodal mechanism of action also involving changes in the organization of the microtubule cytoskeleton. J. Med. Chem. 2019, 62, 5176–5190. [Google Scholar] [CrossRef] [PubMed] Macias, F.J.; Deo, K.M.; Pages, B.J.; ...
[71] reported that curcumin was able to shut down the pathways of MCF7 and SUM159 sphere-forming cells. The study revealed that the phytochemical kills BCSCs because of the downregulation of the two pathways [71]. Resveratrol, a polyphenolic compound found in cranberries, peanuts, and ...