of recombinant strain, protein expression and purification, enzyme preparation, biocatalysis, chemical synthesis of drugs, antisense oligonucleotide drug synthesis. The Company has a molecular biology laboratory, pilot scale fermentation, catalytic synthesis workshop, antisense oligonucleotide drug pilot test ...
Medicilon's peptide synthesis research team is closely focused on the topic of peptide drug research and is committed to solving the core problems that limit the development and application of peptide drugs.
Learn about the definition of chemical synthesis in chemistry. Understand how important it is for life, and see examples of chemical synthesis and...
Novel antiblastic Ru(III)-, Cu(II)- and Au(III)-based coordination compounds: from rational design, synthesis and physico-chemical characterization to nano... There is an essential contribution of inorganic medicinal chemistry in the pharmacopeia. In particular, platinum-based drugs revolutionized ...
Chemical syntheses, modulators of chemotherapeutic receptor activity; drug synthesis including these receptors; and drugs used to treat inflammation, allergy and autoimmunity.Pireridinilo substituted Compounds, Pharmaceutical Composition and Method for the treatment of osteoarthritis and other diseases.SANTELLA ...
Analgesic activity is better than similar drugs, and the length of holding time and toxic side effects are little, secure and better tolerance. At first in, France's listing formally entered China in 1973, the eighties, developed now multiple formulations such as an oral tablet, paster, ...
Isatin, with the chemical name 1H-indole-2,3-dione skeleton, is an important pharmaceutical intermediate that can be used to prepare antitumor drugs, antibacterial drugs, and antimalarial drugs. See also Synthesis of Indoxyl Indoxyl exists in two possible tautomeric equilibria with keto and enol for...
Lipinski, C. A. Overview of hit to lead: the medicinal chemist's role from HTS retest to lead optimisation hand off.Top.Med. Chem.5, 1–24 (2009). ArticleGoogle Scholar Wipke, W. T. & Rogers, D. Artificial intelligence in organic synthesis. SST: starting material selection strategies....
study recently published online in Nature, a specially designed "chiral catalyst" is used to oxidize hydrocarbons into multifunctional compounds that are obtained in high purity and are readily converted into an assortment of molecules that will streamline the synthesis of future pharmaceutical drugs. ...
News & Views14 Jun 2024Nature Synthesis Volume: 3, P: 935-936 Reversing the charge of lysine by genetic code expansion Posttranslational modifications alter the structure and function of proteins. Now, genetic code expansion enables encoding of ε-N-succinyllysine and ε-N-glutaryllysine residues...