The methylation of intracisternal A-type particle () sequences is maintained during . Methylation suppresses expression and the potential for by retrotrans... F Gaudet,WM Rideout,A Meissner,... - 《Molecular & Cellular Biology》 被引量: 296发表: 2004年 Stage-specific alterations of DNA methylt...
Using Change in Local DNA Sequence Complexity as a Pointer to the Mechanism of Mutagenesis in Inherited Diseasesequence complexitymicro-deletionmicro-insertionindelmutagenesisThe vast majority of mutations causing human genetic disease are single base-pair substitutions and micro-deletions. However, a ...
Clownfishes live in social assemblages as pairs or social groups consisting of a dominant female, always the largest in size, surrounded by a male and a variable number of immature juveniles of smaller size8. Clownfish species display a strong social hierarchy based on size9. These hierarchies f...
Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non-recurrent CNVs). Non-recurrent CNVs frequently show microhomology at their end-points, and can have a co...
for the change of a gene within the genome by homologous recombination of intact mammalian cells leads to a dna sequence which homolog to changing gene is, however, in at least one nucleotide mutation, deletion or insertion of the sequence differs by mikroinjektion in corresponding cells and wins...
DNA sequence-dependent conformational changes induced by the minor groove binder, distamycin, have been evaluated by polyacrylamide gel electrophoresis. The distamycin binding affinity, cooperativity, and stoichiometry with three target DNA sequences that have different sizes of alternating AT sites, ATAT,...
The mutation was constructed by using a synthetic oligodeoxynucleotide that differs in sequence by one base from the wild-type sequence of 16S rRNA. This oligonucleotide was used as a primer on single-stranded DNA of phage M13, into which was cloned a specific region of DNA encoding 16S rRNA....
根据第四段The company has found the genetic code of the extinct animals from their dead bodies.It will change the DNA of present living animals to make them close to the animal of the past.The Nicobar pigeon,a kind of bird,will be used as the genetic base for the ...
Log in Learn about institutional subscriptions Read our FAQs Contact customer support Data availability High-throughput sequencing data generated during the study (CHANGE-seq, GUIDE-seq, ATAC-seq, histone modification ChIP–seq) are available from the NCBI Sequence Read Archive and Gene Expression Omnib...
However, clear examples of genetic changes via adaptation are limited. We explore evolutionary responses to climate change in the endangered southwestern willow flycatcher (Empidonax traillii extimus) through whole-genome comparisons between historical specimens, collected from 1888 to 1909 near San Diego,...