cGMP-PKG signaling pathway Cyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated intracellular cGMP level exerts its physiological action through two forms ...
背根节慢性压迫模型小细胞交感敏化的no-cgmp-pkg信号通路分析-no - cgmp - pkg signal pathway analysis of sympathetic sensitization of small cells in chronic dorsal root ganglion compression model 第四军医大学硕士学位论文第四军医大学硕士学位论文 HYPERLINK \l _bookmark0 3 实验结果 41 HYPERLINK \l _...
内容提示: Contents lists available at ScienceDirectBBA - Molecular Basis of Diseasejournal homepage: www.elsevier.com/locate/bbadisGenes of the cGMP-PKG-Ca 2+ signaling pathway are alternatively spliced incardiomyopathy: Role of RBFOX2Xianxiu Wan a , KarryAnne Belanger b , Steven G. Widen b ...
Activation of cGMP-PKG signaling pathway contributes to neuronal hyperexcitability and hyperalgesia after in vivo prolonged compression or in vitro acute ... ZJ Huang,LI Hao-Chuan,S Liu - 《Acta Physiologica Sinica》 被引量: 13发表: 2012年 Upregulation of Sodium Channel Nav1.3 and Functional In...
cGMP/PKG-I Pathway–Mediated GLUT1/4 Regulation by NO in Female Rat Granulosa Cells 来自 掌桥科研 喜欢 0 阅读量: 29 作者:Y Tian,H Dai,K Xu,W Liu,X Weng,X Hu,C Zhang 摘要: Nitric oxide (NO) is a multifunctional gaseous molecule that plays important roles in mammalian reproductive ...
Cardiac hypertrophy is an abnormal enlargement of heart muscle. It frequently results in congestive heart failure, which is a leading cause of human death. Previous studies demonstrated that the nitric oxide (NO), cyclic GMP (cGMP), and protein kinase G (PKG) signaling pathway can inhibit cardia...
Note: cGMP-PKG, cGMP-dependent protein kinase (PKG) signaling pathway; ADRA1A, adrenoceptor alpha 1A; SLC8A1, solute carrier family 8 member A1; EDNRB, Endothelin Receptor Type B; ATP1A2, ATPase Na+/K+ transporting subunit alpha 2; KCNJ8, Potassium inwardly rectifying channel subfamily J mem...
Moreover, BBR enhanced NO and cGMP concentrations, leading to the activation of the NO/cGMP/PKG signaling via activating AKT1/MAPK axis. The in vivo experiments were consistent with the findings obtained in vitro. Hence, BBR represents a drug candidate for diabetic patients and its mechanism of...
in addition to increasing melanogenesis. PPIX functions primarily by activating the guanylate cyclase (GC) and cyclic guanosine 3', 5'-monophosphate/protein kinase G (cGMP/PKG) signaling pathways. Once activated, these pathways increase tyrosinase ...
www.nature.com/scientificreports OPEN received: 22 March 2016 accepted: 20 July 2016 Published: 11 August 2016 Urothelium muscarinic activation phosphorylates CBSSer227 via cGMP/PKG pathway causing human bladder relaxation through H2S production Roberta d'Emmanuele di Villa Bianca1,2,*, Emma...