#OxHARP trial (Oxford Haemodynamic Adaptation to Reduce Pulsatility) was a double-blind, randomized, placebo-controlled, 3-way crossover trial after nonembolic cerebrovascular events with mild-moderate white matter hyperintensities (WMH), the most prevalent manifestation of cerebral small vessel disease....
;Nogueira, Raul G. 259-264 Spontaneous Spinal Epidural Hematoma Mimicking Stroke and Its Outcome post Intravenous Thrombolysis Szeto, Cheuk Ling Charing;Hui, Kwok Fai 265-269 Cerebral Microvascular and Macrovascular Disease Risk Factors and COVID-19 Progression Cimolai, Nevio 270-271 ...
small vessel cerebrovascular pathology identified by magnetic resonance imaging is prevalent in alzheimers disease and mild cognitive impairment: a potenti... There is evidence that Alzheimer's disease (AD) has significant cerebrovascular etiopathogenesis. Understanding potentially modifiable risk factors for ...
19. One recent study has reported a benefit of statin and BP-lowering medication using a more sensitive digit-symbol substitution score in healthy people without any known cardiovascular disease20. Overall, however, to the best of our knowledge there has been no clear demonstration of a ...
Shi Y, Wardlaw JM. Update on cerebral small vessel disease: a dynamic whole-brain disease. Stroke and vascular neurology. 2016 Sep:1(3):83-92. doi: 10.1136/svn-2016-000035. Epub 2016 Oct 25[PubMed PMID: 28959468] [6] Estruch R, Ros E, Martínez-González MA. Mediterranean diet for ...
In the brain, increased arterial stiffness can damage the arterial endothelium in small arteries and can, over time, produce a pathology known as small vessel disease (SVD)2. The brain, in particular, is highly vulnerable to SVD, as the blood flow to the sub-surface brain structures is comp...
Cilostazol and isosorbide mononitrate for the prevention of progression of cerebral small vessel disease: baseline data and statistical analysis plan for the LACunar Intervention Trial-2 (LACI-2) (ISRCTN14911850). medRxiv. 2022.05.31.22275743. doi:10.1101/2022.05.31.22275743Google Scholar 12. Bath...
Early cerebral small vessel disease and brain volume, cognition, and gait. Ann Neurol. 2015;77(2):251-261. doi:10.1002/ana.24320PubMedGoogle ScholarCrossref 55. Naveed M, Zhou QG, Han F. Cerebrovascular inflammation: a critical trigger for neurovascular injury? Neurochem...
Small Vessel Cerebrovascular Pathology Identified by Magnetic Resonance Imaging Is Prevalent in Alzheimer's Disease and Mild Cognitive Impairment: A Potent... magnetic resonance imagingneuropsychological testingsmall vessel pathologyThere is evidence that Alzheimer's disease (AD) has significant cerebrovascular...
Objectives: To investigate the correlation and predictive value of serum matrix metalloproteinase-9 (MMP-9) level with cognitive dysfunction and total imaging load in patients with cerebral small vessel disease (CSVD). Conclusion: Serum MMP-9 level and tHcy level were significantly correlated with cog...