Cerebral small vessel disease (cSVD) is a leading cause of ischaemic and haemorrhagic stroke and a major contributor to dementia. Covert cSVD, which is detectable with brain MRI but does not manifest as clinical
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among elderly individuals and is recognized as a major vascular contributor to dementia, cognitive decline, gait impairment, mood disturbance and stroke. However, clinical symptoms are often highly inconsistent in nature and severity...
Small-vessel disease Brain Ischemic stroke Hemorrhage Vascular dementia 1. Anatomy of cerebral small vessels Small blood vessels include arterioles, capillaries, and venules [1]. They are found ubiquitously throughout the human body, including the brain and heart [2]. These small vessels have been...
Recent small subcortical infarcts (RSSI) are considered an acute manifestation of cerebral small vessel disease (CSVD). We assessed whether the topography of RSSI was related to CSVD markers on magnetic resonance imaging (MRI). Material and methods We screened the local registries of two independent...
脑小血管病(cerebral small vessel disease, CSVD)是指由于小动脉、微动脉、微静脉和毛细血管病变所导致的脑皮质下深部结构损害而产生的一组异质性较大的症候群。 影像学以腔隙性梗死(Lacunar Infarcts, LI)、白质病变(white matter lesions, WML)、脑微出血(cerebral microbleeds, CMB)和扩大的血管周围间隙(enlarg...
Cerebrovascular disease is a major burden to individuals and their communities worldwide. Stroke is one of the leading causes of death and disability, and the prevention and treatment of stroke can be improved with a better understanding of its causation. Cerebral small vessel disease (SVD) is a...
脑小血管病(cerebral small vessel disease,cSVD)泛指上述小血管的各种病变所导致的一系列临床、认知、影像学及病理表现的综合征。
,脑小血管分布示意图,脑小血管病(cerebralsmallvesseldisease,CSVD),概述:脑小血管功能:1、血液运输:管壁的病变、血管的迂曲以及数量的变化会导致血供障碍2、脑血流量调节:小动脉舒缩脑血供储备能力的基础3、血脑屏障:脑小血管内皮细胞与小血管紧密连接构成了血脑屏障的核心部位4、细胞间液生成及回流:细胞间液及...
Small vessel disease (SVD) is responsible for brain chronic circular disorder, and accounts for 20%-30% cases of ischemic stroke as well as cerebral hemorrhage, and to a great extent, encephalopathy. Binswanger's disease and multiple small strokes, which are common in older people, are also ...
to directly visualise these cerebral small vessels on neuroimaging in life[32], advances in imaging allow us to identify the brain parenchymal sequelae of SVD. These can be correlated with clinical markers of cognition, to give insight into how these small vessel processes result in disease. ...