IGF2BP3/HIF1A/YAP signaling plays a role in driving acute-on-chronic liver failure through activating hepatocyte reprogramming Ke Cheng, Shu Liu, Cai Li, Yujun Zhao, Qiang Wang Article 110727 select article Cell consequences of loss of function of the epigenetic factor EHMT1 ...
3 July 2023 Mechanisms of Interorgan Communication and Impact on Pathophysiology Edited byMichael Tranter,Kristin Stanford 3 July 2023 Underlying molecular pathways in urological cancer progression and therapy resistance Edited byGautam Sethi,Milad Ashrafizadeh,Yuzhuo Wang,Francesco Crea,Navid Rabiee ...
2023, Aging Cell Obesity-related kidney disease: Beyond hypertension and insulin-resistance 2023, Frontiers in Endocrinology Cellular senescence and acute kidney injury 2022, Pediatric Nephrology TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis 2022, Frontiers in Pharmacology Induction of Accelerate...
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9b, c). Besides, the mean nuclear intensities of IRF3, IRF7, and nuclear factor kappa B (NF-κB), major effectors in pattern recognition receptor (PRR) signaling37, were not increased in the neighbors (Supplementary Fig. 9d). This also excludes these pathways unless the virus blocked the...
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Wnt/beta-Catenin signaling in development and disease. Cell 127, 469–480 (2006). Article PubMed CAS Google Scholar Thisse, B. & Thisse, C. Functions and regulations of fibroblast growth factor signaling during embryonic development. Dev. Biol. 287, 390–402 (2005). Article PubMed CAS ...
According to the above conclusions, we speculated that the activation of NOX2 by CVC1302 is related to the p38α MAPK signaling; however, whether p38α MAPK signaling is the only factor causing the production of NOX2 induced by CVC1302 requires further research using p38α-deficient DCs. ...
Future improvements can involve the integration of complex signaling pathways, immune responses, hypoxia, nutrient transport, and mechanical stresses, such as oncotic pressure or laminar flows affecting the tumor surface. In conclusion, the HCA model represents a promising tool for investigating the ...