Cellular senescence and itseffector programs. Salama R,Sadaie M,Hoare M, et al. Genes and Development . 2014Salama R, Sadaie M, Hoare M, Narita M. 2014. Cellular senescence and its effector programs. Genes & Development 28:99-114. DOI: https://doi.org/10.1101/gad.235184.113, PMID: ...
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Salama R, Sadaie M, Hoare M, Narita M (2014) Cellular senescence and its effector programs. Genes Dev 28:99–114 ArticleCASPubMedPubMed CentralGoogle Scholar Santelli A, Sun IO, Eirin A, Abumoawad AM, Woollard JR, Lerman A, Textor SC, Puranik AS, Lerman LO (2019) Senescent kidney ...
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Cellular senescence and its effector programs. Genes Dev 2014; 28: 99–114. 14. Bozorgi SS, Proctor GB, Carpenter GH. Rapamycin delays salivary gland atrophy following ductal ligation. Cell Death Dis 2014; 5: e1146. 15. Silver N, Proctor GB, Arno M, Carpenter GH. Activation of mTOR ...
Classically, senescence, particularly in human cells, involves t... R Salama,M Sadaie,M Hoare,... - 《Genes Dev》 被引量: 379发表: 2014年 Cellular senescence and its effector programs Cellular senescence is a stress response that acco Salama,R.,Sadaie,... - 《Genes & Development A ...
senescence[4]. Oxidative damage and telomeric erosion can activate the DNA damage response (DDR), a signaling pathway in which ATM, ATR, CHK1, and CHK2 kinases activate various cell cycle targets including p53 and its downstream targetp21[10]. Both p16 and p21 as well as other cell cycle...
its pathogenesis. In this review, we systematically summarize the cross-talk between cellular senescence and inflammation in OA. We begin by focusing on the mechanisms and hallmarks of cellular senescence, summarizing evidence that supports the relationship between cellular senescence and inflammation. We...
The oncogenic protein Ras and its effectors, such as activated mutant RAF, MEK, and BRAF, have all been shown to cause senescence[7–9]. This form of cellular senescence is similar to the Hayflick limit; however, in contrast to Hayflick's obser- * To whom correspondence should be ...
its pathogenesis. In this review, we systematically summarize the cross-talk between cellular senescence and inflammation in OA. We begin by focusing on the mechanisms and hallmarks of cellular senescence, summarizing evidence that supports the relationship between cellular senescence and inflammation. We...