The biology of normal cell transformation into cancer cells has been explained at the genetic/epigenetic and proteomic levels. However, reasons (usually random) for cancer initiation, development, and progression are not fixed and rather can be considered as unified perplexing dysregulation of crucial ...
Here, the authors show that loss of the androgen receptor (AR) in fibroblasts causes nuclear alteration and transforms them into tumor-promoting CAFs through increased phosphorylation of lamin A/C. Soumitra Ghosh Jovan Isma G. Paolo Dotto ResearchOpen Access12 Sept 2024 Nature Communications ...
DANCE is the first standard, generic, and extensible benchmark platform for accessing and evaluating computational methods across the spectrum of benchmark datasets for numerous single-cell analysis tasks. Currently, DANCE supports 3 modules and 8 popula
To mitigate batch effects between replicates we used Seurat’s integrated analysis approach that transforms datasets into a shared space using pairwise correspondences (or “anchors”)40. Anchors were first defined using FindIntegrationAnchors (dims = 1:40) and the data were then integrated (...
Sickle cell disease (SCD) is a group of genetic disorders in which an abnormal hemoglobin molecule (hemoglobin S) transforms red blood cells into a “sickle-shaped” cell.
I’ve had the pleasure of chatting with DeityVengy, a YouTuber-turned-modder who has been working on the absolutely massive Star Wars Genesis: A total conversion modlist for Starfield that transforms the Bethesda title into the ultimate Star Wars open-world RPG. So grab some blue milk, ...
New Technology Transforms The Synthesis Of Cell Membranes Into A Controlled ProcessMika Ono
In the last few decades, the role of cancer stem cells in initiating tumors, metastasis, invasion, and resistance to therapies has been recognized as a potential target for tumor therapy. Understanding the mechanisms by which CSCs contribute to cancer pr
Amphibian uro- deles exhibit the most complete and drastic regenerative capabilities among tetrapods, with most species retaining the ability to regrow near-perfect copies of both limbs and tails following amputation80–82. Conversely, lizards are the only known amniotes and the closest rela- tives...
Cell migration, an essential process for normal cell development and cancer metastasis, differs from a simple random walk: the mean-square displacement (〈(Δr)2(t)〉) of cells sometimes shows non-Fickian behavior, and the spatiotemporal correlation func