During division, eukaryotic cells undergo a dramatic, complex and coordinated remodelling of their cytoskeleton and membranes. For cell division to occur, chromosomes must be segregated and new cellular structures, such as the spindle apparatus, must be assembled. Pre-existing organelles, such as the...
Besides triggering cell death, mitochondrial permeabilization has been reported to engage nuclear factor-κB anti-tumor signaling to cause tumor regression in vivo44. During transformation, developing tumor cells experience a variety of stresses such as hyperproliferation, excessive DNA damage, decreased su...
BE5 served as both the initiating cell during nodular formation and the transitional cell during the transformation from luminal epithelial (LE) to BE cells. A distinguishing characteristic of the BE5 cell subgroup in patients with BPH was its heightened hypoxia and upregulated expression of FOS. ...
The liver is unique in its ability to regenerate from a wide range of injuries and diseases. Liver regeneration centers around hepatocyte proliferation and requires the coordinated actions of nonparenchymal cells, including biliary epithelial cells, live
Overview of the current issues in austenite to ferrite transformation and the role of migrating interfaces therein for low alloyed steels Solid state phase transformations in metals, and more precisely the science of transformation interfaces, is a key point to understand the formation of nan... M...
Similarly, once activated to grow, the oocyte embarks on a phase of dramatic molecular and morphological transformation, involving a greater than fivefold increase in volume, synthesis and reorganization of nuclear and cytoplasmic organelles [11,12,13], and the establishment of the oocyte epigenome ...
cell polarity single-cell biochemistry C. elegans PAR proteins PAR-3 SiMPull sc-SiMPull PLK-1 cortical flow Introduction Regulation of protein-protein interactions is a widespread mechanism for control of cell signaling. In one common signaling paradigm, a cellular event triggers binding (or unbind...
Complete data were collected and analysed from all four experimental trials by all 13 participants, giving a total of 52 data sets. The data means and standard deviations were proportional, so all of the subjective workload data were transformed using the log(x) transformation. The MRT scores ...
The transformation of the ovary into a fruit after successful completion of pollination and fertilization has been associated with many changes at transcriptomic level. These changes are part of a dynamic and complex regulatory network that is controlled by phytohormones, with a major role for auxin....
Data expressed as a percentage were normalized by arcsine square root transformation. Data were analyzed using two-way repeated-measures ANOVA, followed by the Friedman test for post hoc comparison of means. To analyze protein gels, the statistical component of the SameSpots software was used, as...