During division, eukaryotic cells undergo a dramatic, complex and coordinated remodelling of their cytoskeleton and membranes. For cell division to occur, chromosomes must be segregated and new cellular structures, such as the spindle apparatus, must be assembled. Pre-existing organelles, such as the...
Counting cells is often a necessary but tedious step for in vitro cell culture. Consistent cell concentrations ensure experimental reproducibility and accuracy. Cell counts are important for monitoring cell health and proliferation rate, assessing immortalization or transformation, seeding cells for subsequent...
BE5 served as both the initiating cell during nodular formation and the transitional cell during the transformation from luminal epithelial (LE) to BE cells. A distinguishing characteristic of the BE5 cell subgroup in patients with BPH was its heightened hypoxia and upregulated expression of FOS. ...
The transformation of inorganic constituents in annual biomass was experimentally investigated at grate-combustion conditions. A laboratory fixed-bed reactor was applied to obtain quantitative information of the release of Cl, K, and S to the gas phase from six distinctively different annual biomass fue...
Aging is a global challenge, marked in the lungs by function decline and structural disorders, which affects the health of the elderly population. To explore anti-aging strategies, we develop a dynamic atlas covering 45 cell types in human lungs, spannin
The stage III foci eventually gave rise to subtetraploid tumorigenic cell lines. The studies suggested that during in vitro development of neoplastic transformation in salivary gland epithelium, tetraploids were generated that then underwent a period of chromosome instability and loss. Evidence was also...
Many intracellular pathogens, such as mammalian reovirus, mimic extracellular matrix motifs to specifically interact with the host membrane. Whether and how cell-matrix interactions influence virus particle uptake is unknown, as it is usually studied fro
Mezard C,Nicolas A.Homologous, homeologous, and illegitimate repair of double-strand breaks during transformation of a wild-type strain and a rad52 ... C Mezard,A Nicolas - 《Mol.cell.biol》 被引量: 109发表: 1994年 Characterization of double-strand break-induced recombination: homology requ...
Similarly, once activated to grow, the oocyte embarks on a phase of dramatic molecular and morphological transformation, involving a greater than fivefold increase in volume, synthesis and reorganization of nuclear and cytoplasmic organelles [11,12,13], and the establishment of the oocyte epigenome ...
transformation of human endometrium at single-cell resolution across the menstrual cycle, resolving cellular heterogeneity in multiple dimensions. We profiled the behavior of seven endometrial cell types, including a previously uncharacterized ciliated cell type, during four major phases of endometrial ...