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Victor Ambroswas born in 1953 in Hanover, New Hampshire, USA. He received his PhD from Massachusetts Institute of Technology (MIT), Cambridge, MA, in 1979 where he also did postdoctoral research 1979-1985. He became a Principal Investigator at Harvard University, Cambridge, MA in 1985. He wa...
Thus, we hypothesize that the reversible CRM1 inhibitor S109 may induce radiosensitivity in glioblastoma (GBM) by regulating the NF-κΒ signaling pathway. Methods This study utilized the cell counting kit-8 (CCK-8), 5-ethynyl-2′-deoxyuridine (EdU), and colony formation assay to evaluate ...
Finally, the cells were visualized with ECL plus reagents (Cell Signaling Technology, Danvers, MA, USA). Cell culture One normal thyroid follicular epithelial cell line (Nthy-ori 3–1), four PTC cell lines (K-1, KTC-1, TPC-1, and B-CPAP), one anaplastic thyroid carcinoma cell line (...
Cell Signaling Technology product type : antibody product name : Akt3 (L47B1) Mouse mAb catalog : 8018P quantity : 40 ul price : 123 USD clonality : monoclonal host : mouse reactivity : human,mouse,rat application : western blot more info or order: ...
D, L-sulforaphane-L-cysteine (SFN-Cys) (sc-207499) was purchased from Santa Cruz Biotechnology (Dallas, Texas, USA). Anti-p-ERK1/2 (9101S), anti-ERK1/2 (9102S), anti-LAMP1 (15665), and PD98059 (9900S) were obtained from Cell Signaling Technology (Danvers, MA, USA). Anti-Stath...
Technology Transfer: Biotech and Pharmaceutical, therapeutics, Tissue Engineering and Regenerative Medicine, Tissue Microenvironment, Tolerance-inducing Autoimmune Disease Therapeutics, Transcriptomics, Transformative Technologies in Healthcare, Translational Research, tyrosine decarboxylases, Ubiquitin, Ubiquitinylation...
MSCs are known to reduce brain damage through their anti-inflammatory and anti-apoptotic properties, mainly via MSC-secreted exosomes mediated paracrine signaling [27]. Intraperitoneally administered HUCMSCs have demonstrated neuroprotective effects in Alzheimer’s disease [33]. These protective effects are...
Primary antibodies against TLR4, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 4 (NOX4), glutathione peroxidase 4 (GPX4), and ferritin heavy chain 1 (FTH1) were obtained from Cell Signaling Technology (Beverly, MA, USA). Primary antibodies against NLRP3, ASC, pro-caspase1 and ...
The transfected GC cells, and grafted tumor cells, were lysed with RIPA buffer (Cell Signaling Technology, Boston, MA, USA). Equal amounts of protein lysates were run on 10% sodium dodecyl sulfate–polyacrylamide gel electrophoresis gels, and transferred to polyvinylidene fluoride membranes. The me...