It is an exciting time for lipid metabolism and membrane cell biologists as technological progress has increased our ability to study lipids in cells. We asked leaders studying lipid cell biology from different perspectives to share what questions they are most interested in and what tools they beli...
For a drug to be absorbed, reach its site of action, and eventually be eliminated, it must cross one or more biologic membrane barriers. Because such barriers to drugs behave similarly, the cell membrane can serve as an example for all. The cell membrane is composed of a bimolecular sheet...
Plasma membrane CellMask Green Plasma Membrane Stain CellMask Orange Plasma Membrane Stain CellMask Deep Red Plasma Membrane Stain Short-term (10-90 minutes, can image longer but will internalize) Reactive oxygen species CellROX Green Reagen...
Her undergraduate work revealed that the cell membrane of macrophages exhibits undulations that impede their adhesion, which may be critical for their ability to fight pathogens in human body. For her PhD studies, Alexandra moved on to the University of California, Santa Barbara where she worked ...
After 24 h, GFP-labeled tumor cells that had migrated through the membrane were visualized and quantified using a fluorescent microscope. Inflammasome activation LPS and ATP were utilized to activate the NLRP3 inflammasome, MCC950 served as an inhibitor of NLRP3 inflammasome activation. HA1800 cells...
Mesenchymal stem cells enhance ovarian cancer cell infiltration through IL6 secretion in an amniochorionic membrane based 3D model. J. Transl. Med. 2013, 11, 28. [Google Scholar] [CrossRef] [PubMed] [Green Version] Nii, T.; Tabata, Y. Immunosuppressive mesenchymal stem cells aggregates ...
Active transport may also occur in an indirect or secondary fashion. For example, a membrane pump may move sodium across its concentration gradient from one side of the membrane to the other, out of the cell. When the sodium ion diffuses back through in the other direction, it might carry...
a real example of cell communication 91 2019-04 5 membrane transport in cells- symport, antiport, co-transport 88 2019-04 6 electron transport chain 63 2019-04 7 photosynthesis light reaction calvin cycle electron transport 124 2019-04
Common variable immunodeficiency (CVID), the most prevalent symptomatic primary immunodeficiency, displays impaired terminal B-cell differentiation and defective antibody responses. Incomplete genetic penetrance and ample phenotypic expressivity in CVID
the retinal layers and were not morphologically distinct from other CD11b+cells. The differences in the localization and appearance of MHCII+cells in these various models of degeneration may reflect differences in the site of infiltration, either across Bruch’s membrane and RPE, or, as in the ...