The data presented here demonstrate a new approach to the visualization and quantification of gelatin degradation by a variety of cell types at multiple time points and following treatment with modulators of invadopodia formation. Such assays provide a convenient, flexible system for monitori...
attachment of tumor cells to the matrix, degradation of the matrix and tumor cell migration through the matrix (Dedhar and Saulnier 1990). These in vitro phenomena are apparently due to the active mobility of tumor cells. Therefore, we believe that in- testinal-type carcinomas are more ...