Cell death: From apoptosis to necrosisFelix Cheung
Read on to delve deeper into the mechanisms and implications of necrosis and apoptosis. What is Cell Apoptosis? Programmed cell death is called apoptosis, a regular growth, and development mechanism within an organism. This process is also known as “cellular suicide” because the cell takes part...
Cell death terminates normal cellular functions, including respiration, metabolism, growth and proliferation. Cell death can be non-programmed, for example as the result of accidental injury or trauma, or programmed. Types of programmed cell death include anoikis, apoptosis, autophagy, necrosis, necropt...
Browse broader subjects Cell biology Browse narrower subjects Apoptosis Autophagy Entosis Necroptosis Browse Cell death across other nature.com journals Previouspage page1 page2 page3 … page47 Nextpage Cell Death & Disease(Cell Death Dis) ISSN2041-4889(online)...
The question whether cell death is immunogenic or not is not solved by the mode of dying (e.g.,apoptosisvs necrosis), but rather by the premortem stress responses that precede the final disintegration of the cell. For example, autophagy is required for virus-infected or chemotherapy-killed c...
ophagy and Necrosis Keystone Symposia : Cell Death Pathways : Apoptosis , Autophagy and NecrosisKeystone Symposia : Cell Death Pathways : Apoptosis , Autophagy and NecrosisMetabolism, JointProgression, CancerAlbert, Matthew LPasteur, InstitutKinases, Tyrosine...
8B). These findings indicate that, although apoptosis is activated during simulated I/R as evidenced by cytochrome c release and DNA laddering, cell death does not require cytochrome c release in this model. 3.9. Temporal relationship between PI uptake and cytochrome c release HeLa cells stably ...
a nomenclature to distinguish the many and often intercrossed cell death pathways has been proposed.2 A dichotomy has long dominated the general understanding of how dying cells affect their surroundings: necrosis, regarded as a passive and highly inflammatory form of cell death, and apoptosis, cons...
Apoptosis was long thought to be the only regulated cell death pathway. In addition, its counterpart necrosis was considered to be rather ‘clumsy’ and to culminate with the loss of membrane integrity and passive leakage of intracellular contents. It has now become clear that a nonapoptotic form...
Based on morphological examinations and the DNA fragmentation status of dead cells, cell death was initially classified as “programmed” apoptosis [2] and “accidental” necrosis [3] in mammalian cells. However, decades of research in the field have conceptually advanced our understanding of cell ...