Cell death terminates normal cellular functions, including respiration, metabolism, growth and proliferation. Cell death can be non-programmed, for example as the result of accidental injury or trauma, or programmed. Types of programmed cell death include anoikis, apoptosis, autophagy, necrosis, necropt...
Cell death: From apoptosis to necrosisFelix Cheung
It has long been asserted that programmed cell death (PCD) plays critical roles in development and homeostatic maintenance of virtually every tissue in the body. Apoptosis is the most well-characterized PCD to date, but recently mechanisms such as necroptosis, pyroptosis, and ferroptosis have been ...
ophagy and Necrosis Keystone Symposia : Cell Death Pathways : Apoptosis , Autophagy and NecrosisKeystone Symposia : Cell Death Pathways : Apoptosis , Autophagy and NecrosisMetabolism, JointProgression, CancerAlbert, Matthew LPasteur, InstitutKinases, Tyrosine...
Types of Cell Death: Apoptosis, Autophagy, and Necrosis Decades of research have allowed for the detailed characterization and classification of the myriad ways that cells can self-destruct. The demise of a cell can sometimes be caused by rapid overwhelming external influences, as would be the cas...
The question whether cell death is immunogenic or not is not solved by the mode of dying (e.g.,apoptosisvs necrosis), but rather by the premortem stress responses that precede the final disintegration of the cell. For example, autophagy is required for virus-infected or chemotherapy-killed c...
Although apoptosis resistance is a hallmark of many cancer cells,32 some such cells remain sensitive to other cell death processes, including necrosis.33 Thus, a better understanding of the mechanisms underlying necrosis is important, as it could help to elaborate novel therapeutic strategies. Here ...
Based on morphological examinations and the DNA fragmentation status of dead cells, cell death was initially classified as “programmed” apoptosis [2] and “accidental” necrosis [3] in mammalian cells. However, decades of research in the field have conceptually advanced our understanding of cell ...
Browse broader subjects Cell biology Browse narrower subjects Apoptosis Autophagy Entosis Necroptosis Browse Cell death across other nature.com journals Previouspage page1 page2 page3 … page47 Nextpage Cell Death & Disease(Cell Death Dis) ISSN2041-4889(online)...
a nomenclature to distinguish the many and often intercrossed cell death pathways has been proposed.2 A dichotomy has long dominated the general understanding of how dying cells affect their surroundings: necrosis, regarded as a passive and highly inflammatory form of cell death, and apoptosis, cons...