Cell death is essential for maintaining homeostasis during development by eliminating senescent, damaged infected and aberrant cells [1,2]. The process can be non-immunogenic (apoptosis) and immunogenic and pro-
In the early to mid-19th century, cellular death, also known as necrosis, was reported by Carl Vogt and Rudolf Virchow, among others4,5. In 1972, a new type of cell death distinct from necrosis, called apoptosis, was reported by John Kerr6. Since then, many other types of cell death ...
Cell death is essential for maintaining homeostasis during development by eliminating senescent, damaged infected and aberrant cells [1,2]. The process can be non-immunogenic (apoptosis) and immunogenic and pro-inflammatory (necrosis) [3]. The regulated necrosis is modulated by the genetically program...
Apoptosis Cell Death Cell fate Cell Types Mitosis Plant Cell Death Abbreviations DNA: Deoxyribonucleic acid DAMPs: Damage-associated molecular patterns TNF-α: Tumor necrosis factor-α NK: Natural killer cells PCD: Programmed cell death IAP: Inhibitors of apoptosis proteins BIR: Baculovirus ...
Cell death, serving as a crucial regulatory mechanism, significantly contributes to the maintenance of the body’s internal homeostasis and the equilibrium of cell populations [7]. In recent years, there has been significant progress in the development of pharmaceutical agents that specifically target ...
In recent years, programmed cell death (PCD) is considered to be a critical process after SCI, and various forms of PCD were discovered in recent years, including apoptosis, necroptosis, autophagy, ferroptosis, pyroptosis and paraptosis. Unlike necrosis, PCD is known as an active cell death ...
Organellophagy regulates cell death Organellophagy and cell death in inflammatory diseases Conclusions and clinical perspectives Compliance with ethics requirements Declaration of competing interest Acknowledgements References VitaeShow full outline Figures (6) Tables (2) Table 1 Table 2Journal...
protein activation cascades and modulation of gene expression. Although programmed cell death has been usually identified as a synonymous of apoptosis, it also includes different caspase-independent death programs such as autophagy,paraptosis,necroptosisormitotic catastrophe(Broker et al., 2005; de Brui...
cell death. This form of cell death can take various forms, such as ferroptosis, apoptosis, necroptosis, pyroptosis, paraptosis, parthanatos, and oxeiptosis, each displaying distinct genetic, biochemical, and signaling characteristics. The investigation of oxidative cell death holds promise for the ...
Our results, therefore, supported the idea that CBP, Ku70, BAX, and NOX2 have formed a transcriptional network in the prevention of cell death of necrosis, paraptosis, and apoptosis in human melanoma.doi:10.1038/s41420-021-00417-zLiang Ding...