Cell death: From apoptosis to necrosisFelix Cheung
Cell death terminates normal cellular functions, including respiration, metabolism, growth and proliferation. Cell death can be non-programmed, for example as the result of accidental injury or trauma, or programmed. Types of programmed cell death include anoikis, apoptosis, autophagy, necrosis, necropt...
Read on to delve deeper into the mechanisms and implications of necrosis and apoptosis. What is Cell Apoptosis? Programmed cell death is called apoptosis, a regular growth, and development mechanism within an organism. This process is also known as “cellular suicide” because the cell takes part...
Browse broader subjects Cell biology Browse narrower subjects Apoptosis Autophagy Entosis Necroptosis Browse Cell death across other nature.com journals Previouspage page1 page2 page3 … page47 Nextpage Cell Death & Disease(Cell Death Dis) ISSN2041-4889(online)...
in a hybrid cell death process. This is referred to as the ‘apoptosis–necrosis continuum.’ Two features influencing the position of this continuum are the availability ofcaspasesand intracellular ATP. The path by which a cell dies is controlled in part by the nature of the death signal, ty...
Frank D, Vince JE.Pyroptosis versus necroptosis: similarities, differences, and crosstalk.Cell Death Differ. 2019;26(1):99-114. doi:10.1038/s41418-018-0212-61. Escobar ML, Echeverría OM, Vázquez-Nin GH.Necrosis as Programmed Cell Death. In: Cell Death - Autophagy, Apoptosis and Necrosis....
This is in contrast to the type of cell death known as necrosis, which is characterized by cell swelling, chromatin floccula 接受apoptosis片段的细胞入欣然是的membranebound apoptotic身体由巨噬细胞或邻居细胞phagocytosed并且消化了,无需引起一个激动反应。 这是与细胞死亡对比的种类以坏死著名,描绘为细胞...
3 cell death It is now recognised that cell death can take place in two distinct ways. Apoptosis is mainly the result of a physiological process by which cells are eliminated when they are no longer required by the body. Necrosis, on the other hand, is invariably a pathological consequence ...
The external pathway is mediated by the tumor necrosis factor (TNF) superfamily [30]. As a transmembrane protein, TNF can bind to its ligand on the cell membrane, attract Fas-associated death domain (FADD) proteins in the cytoplasm, form an apoptosis-inducing complex, activate caspase 8, and...
Cell death, in the form of apoptosis, necrosis or autophagy, is involved not only in diseases such as cancer and allergy, but also in the normal process of tissue renewal and development. Thus, the aim of this meeting was to bring researchers from different fields, with a common interest ...