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近日,我院詹丽璇教授团队在Cell Death & Disease期刊发表了题为“A20 negatively regulates necroptosis-induced microglia/macrophages polarization and mediates cerebral ischemic tolerance via inhibiting the ubiquitination of RIP3”的研究论文...
近日，我院詹丽璇教授团队在Cell Death & Disease期刊发表了题为“A20 negatively regulates necroptosis-induced microglia/macrophages polarization and mediates cerebral ischemic tolerance via inhibiting the ubiquitination of RIP3”的研究论文。该研究揭示了在脑缺血后发生坏死性凋亡的神经元调控小胶质细胞/巨噬细胞极...
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death. Trends Biochem Sci. 2017;42(4):245-254. doi:10.1016/j.tibs.2016.10.004 Weinlich R, Oberst A, Beere HM, Green DR. Necroptosis in development, inflammation and disease. Nat Rev Mol Cell Biol. 2017;18(2):127-136. doi:10.1038/...
Mechanisms of Cell Death: Ferroptosis Mechanisms of Cell Death: Pyroptosis Mechanisms of Cell Death: Necrosis & Necroptosis Select References Dickens LS, Powley IR, Hughes MA, MacFarlane M. The 'complexities' of life and death: death receptor signalling platforms. Exp Cell Res. 2012;318(11):1269...
Necroptosis: A novel manner of cell death, associated with stroke (Review).doi:10.3892/IJMM.2017.3279Chenglin LiuKai ZhangHaitao ShenXiyang YaoQing SunGang ChenSpandidos Publications
In multicellular organisms, regulatory cell death is a crucial aspect of growth and development. Ferroptosis, which was postulated roughly ten years ago, is a mode of cell death that differs from apoptosis, autophagy, and pyrodeath. This distinct pattern
Necroptosis is an alternative mode of regulated cell death mimicking features of apoptosis and necrosis. Necroptosis requires protein RIPK3 (previously well recognized as regulator of inflammation, cell survival, and disease) and its substrate MLKL, the crucial players of this pathway. Necroptosis is ...
Cell death can be non-programmed, for example as the result of accidental injury or trauma, or programmed. Types of programmed cell death include anoikis, apoptosis, autophagy, necrosis, necroptosis and pyroptosis. Featured The many paths ascending to ferroptosis In 2012, a study revealed a ...