Posttranscriptional silencing of either ATR or GADD45 leads to nearly complete suppression of the pro-apoptotic and/or cell cycle arrest effect of Vpr.PLANELLES VICENTEANDERSEN JOSHUA L.ZIMMERMAN ERIKCell cycle arrest and apoptosis. Planelles V,Andersen J L,Zimmerman E. . 2011...
L. Cell cycle arrest & apoptosis of epithelial cell line by cytolethal distending toxin positive Campylobacter jejuni. The Indian journal of medical research 129, 418-423 (2009).JAIN, D.; PRASAD, K.N.; SINHA, S.;. Vishwakarma, A.L. Cell cycle arrest & apoptosis of epithelial cell line...
Senescence is defined as a cellular state in which irreversible cell cycle arrest and apoptosis resistance occur. From:Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance,2021 Add to Mendeley Also in subject areas: ...
Chen, J. The cell-cycle arrest and apoptotic functions of p53 in tumor initiation and progression. Cold Spring Harb. Perspect. Med. 6, a026104 (2016). PubMed PubMed Central Google Scholar Chen, H. Z., Tsai, S. Y. & Leone, G. Emerging roles of E2Fs in cancer: an exit from cel...
that DCM-DS significantly up-regulated the expression of pro-apoptotic JNK1, pJNK and down-regulated anti-apoptotic AKT1, ERK1 in MCF-7 cells. Conclusion DCM-DS induced cell cycle arrest and apoptosis in MCF-7 cells via multiple signalling pathways. It shows the potential of DCM-DS to be...
Abieslactone Induces Cell Cycle Arrest and Apoptosis in Human Hepatocellular Carcinomas through the Mitochondrial Pathway and the Generation of Reactive Ox... Lv, Z.-R. Shi et al., "Abieslactone induces cell cycle arrest and apoptosis in human hepatocellular carcinomas through the mitochondrial ...
Moreover, PS1 and PS2 could significantly induce apoptosis and cell cycle G2/M arrest in HepG2 cells, which were at least associated with activation of mitochondrial caspase-dependent and -independent apoptotic cascades, inhibition of cyclin-dependent kinase 1 and PI3K/Akt signaling pathway, and ...
There are several reasons for thinking of apoptosis as a cell cycle phenomenon. First, within the organism, apoptosis is almost exclusively found in proliferating tissues. Second, artificial manipulation of the cell cycle can either prevent or potentiate apoptosis, depending on the point of arrest. ...
In this review, we summarize the anticancer effects of fucoxanthin through several different mechanisms including anti-proliferation, induction of apoptosis, cell cycle arrest and anti-angiogenesis, and its possible role in the treatment of cancer. 展开 关键词: cancer fucoxanthin apoptosis cell cycle ...
细胞周期阻滞(Cell Cycle Arrest)是指细胞在细胞周期中不能顺利从一个阶段进入下一个阶段的现象。这种阻滞是细胞周期调控中的重要机制,对于维持细胞稳态、基因稳定性和防止疾病发生具有重要意义。 一、细胞周期阻滞的定义与意义 细胞周期阻滞通常由于细胞内外信号的缺乏或异常导致。在正常...