Transwell migration assay was used to evaluate whether the M1-polarized macrophage enhanced motility of HCC cells in the presence or absence of NF-κB inhibitor Bay 11-7802. The activation of NF-κB and FAK signaling pathways was examined by Western blot assay. Our results showed that the ...
(2)巨噬细胞(macrophage, MΦ) 通用标志物:CD68 分型:M1、M2 标志物: M1:CD80/CD86/IL-1/IL-12等 M2:CD206/CD301/CD163/IL-10/Arg-1等 2. NK细胞 特点:不依赖抗体和补体即可直接杀伤细胞,活化NK细胞可产生IFN-γ 标志物:CD16、CD56、CD57、CD59、CD11b、CD94等 3. B细胞 特点:分为B1(T细胞...
For example, macrophage-mediated CD48-2B4 signaling can synergize with NKG2D-ligands, resulting in NK cell cytotoxicity and IFNγ production [179]. The CD48-2B4 interaction also complements DNAM-1 signaling in the presence of proinflammatory cytokines from M1-polarizing macrophages, thus activating ...
CD68,MACROPHAGE,110KD,CLONE:PG-M1,MABANTI-HUMAN:FROZEN/PARAFFIN information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
This microenvironment switches the macrophage phenotype from a proinflammatory state (M1) to an anti-inflammatory state (M2).74 Such CD68-positive macrophages are called tumor- associated macrophages (TAMs). TAMs acquire immuno- suppressive properties and inhibit cytotoxic activity of CD8+ T cells in...
CD68,MACROPHAGE,CLONE:PG-M1,MABANTI-HUMAN information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
CD206+ macrophage is a subtype of M2 macrophages which could interact with proinflammatory cytokines in autoimmune diseases and thus might be involved in the pathogenesis [12,13,14,15,16]. However, their role in AGN is not well studied. In this study, we investigate the roles of CD206+ ...
The effects of shiga toxin 1, 2 and their subunits on cytokine and chemokine expression by human macrophage-like THP-1 cells[J]. Toxins (Basel), 2015, 7(10): 4054-4066.[17]ALMATROODI S A, MCDONALD C F, DARBY I A, et al. Characterization of M1/M2 tumour-associated macrophages(...
Koumine regulates macrophage M1/M2 polarization via TSPO, alleviating sepsis-associated liver injury in mice Authors - Gui-Lin Jin View Article Int Immunopharmacol Macrophages regulates the transition of pericyte to peritoneal fibrosis through the GSDMD/IL-1β axis Authors - Qiuyuan Shao View Article ...
Ciclopirox, an iron chelator, can regulate macrophage phagocytosis by depriving iron from macrophages53. PRIMA-1, a mutant p53 reactivator, regulates the polarization of macrophages by inhibiting the NF-κB and STAT1 signaling pathways54. Moreover, trametinib, RDEA119, and selumetinib were the top ...