结果发现,与HD组相比,HCC患者NKG2D+NK细胞和NKG2D+CD56dimNK细胞频率显著下降,而NKG2A+NK细胞和NKG2A+CD56dimNK细胞频率上升(图2)。在术后未复发组和复发组的对比中,术后未复发组的NK细胞、CD56dimNK细胞、NKG2D+NK细胞和NKG2D+...
1、年轻CMV+健康人CD56neg NK比例没有明显变化,而在60岁以上健康老年人中,CD56neg NK细胞只在CMV/EBV双重感染者中显著增多: •CMV/EBV双重感染组CD56neg NK细胞比例升高更为显著•CD56neg NK细胞的增多伴随着CD56dim NK细胞数量的减少•单独CMV或EBV感染组未见CD56neg NK细胞明显增加 2、CD56阴性NK细胞功能...
Immune reconstitu-tion of CD56 (dim)NK cells in individuals with primary HIV-1infection treated with interleukin-2. Michaelsson J,Long B R,Loo C P,et al. The Journal of Infectious Diseases . 2008Michaelsson J,Long B R,Loo C P,et al.Immune reconstitu-tion of CD56 (dim)NK cells in ...
However, the cell-surface expression of programmed death-1 (PD-1) on CD4+ T and CD8+ T cells were markedly elevated in INR group. Moreover, it was found that the proportion and the killing ability of CD56dim NK cells significantly increased in INR patients, and significantly correlated ...
2022年8月4日,重庆医科大学附属第二医院感染病科、重庆医科大学病毒性肝炎研究所、教育部感染性疾病分子生物学重点实验室任红教授和殷文伟研究员合作在《Antiviral Research》(2021 IF=10.103)上发表了题为“Increased ILT2 expression contributes to dysfunction of CD56dimCD16+NK cells in chronic hepatitis B virus...
脐血中CD56~(bright)CD16~(dim) /~-NK细胞亚群的检测 下载积分: 2990 内容提示: 两两比较均存在统计学差异,在内生肌酐清除率尚处于正常范围的 A组,Scy-c 、尿尿 β2-MG 的升高程度更加明显,说明 Scy-c、CRP 、尿β2-MG 对早期肾损伤的灵敏度要优于内生肌酐清除率,与国内一些研究观点相符 [8-9] 。
CD56dimCD16+ NK cells downregulate CD16 following target cell induced activation of matrix metalloproteinases . Leukemia (2007) 21 :356–9.10.1038/sj... B Grzywacz,N Kataria,MR Verneris - 《Leukemia》 被引量: 118发表: 2007年 NK cells downregulate CD16 following target cell induced activatio...
Human immunodeficiency virus-1 (HIV-1) infected patients show a gradual loss of natural killer (NK) cells that correlates with disease progression. However, the effect of HIV-1 infection on different NK cell subsets has not been fully characterized. In healthy individuals most NK cells are CD3...
One cell type, the natural killer (NK) cell, may serve as a bridge between the innate and adaptive immune system, yet its role in pediat- ric sepsis has not been well described. NK cells are small, bone marrow–derived granular lympho- cytes that have the "natural" ability to kill ...
NK cells contribute to anti-tumour immunity, which is traditionally analysed using human peripheral blood NK cells3. In contrast, the role of NK cells in the progression of melanoma to lymph node metastasis has not been investigated. We, therefore, set out to analyse and compare NK cell ...