Expression of CD46 is also highly maintained in many cancers, including bladder cancers, and thus functions as a receptor for many cancer therapeutic viruses. In this study we report a unique role of CD46 as a progression factor of cancer cells in bladder cancers. R...
And the encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I,which protects the host cell from damage by complement. In addition,the encoded protein can act as a receptor for the Edmonston strain of measles virus,human herpesvirus-6,and ...
Consequently, the speciation of Se in such studies is essential for understanding and predicting Se availability for absorption. 展开 关键词: Cadmium Selenium Oxidative stress DNA damage Birth anthropometric measures Saudi Arabia DOI: 10.1016/j.ijheh.2014.08.001 被引量: 20 ...
The KLRK1 has been designated as CD314 and contains a C-type lectin-like domain (CTLD). KLRK1 is also known as: KLR; NKG2D; NKG2-D; FLJ17759; ... RK Gupta,GS Gupta - Animal Lectins: Form, Function and Clinical Applications 被引量: 0发表: 2012年 The DNA damage pathway regulates in...
Earle, A.J., Kirby, T.J., Fedorchak, G.R.et al.Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells.Nat. Mater.19, 464–473 (2020).https://doi.org/10.1038/s41563-019-0563-5 《自然...
奥拉帕利是首个口服多聚二磷酸腺苷核糖聚合酶(PARP)抑制剂药物,作用机理是基于DNA修复损伤机制(DNA damage response,DDR)。已被批准用于四线治疗晚期BRCA+卵巢癌,成为全球首个上市的PARP抑制剂。以及携带BRCA胚系突变的HER2阴性转移性乳腺癌,以及HR...
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Role of oxygen radicals in DNA damage and cancer incidence The development of cancer in humans and animals is a multistep process. The complex series of cellular and molecular changes participating in cancer develo... M Valko,M Izakovic,M Mazur,... - 《Molecular & Cellular Biochemistry》...
Mammalian Bid, Bcl-xL and Puma involve in the reparations of DNA damage. Studies on the functions of Bcl-2 proteins in fish in DNA damage were ... 齐志涛,闫冬,熊凡,... - 《Journal of Hydrobiology》 被引量: 0发表: 2021年 p53上调凋亡调控因子在肿瘤中的作用及其在口腔癌研究中的新进展 家...
1) genetic damage 遗传性损伤 2) Genotoxic damage 遗传毒性损伤 3) Genetic damage 遗传损伤 1. The genetic damage to testicular germ cells and sperms of mice after exposure to Depleted Uranium; 贫铀对小鼠睾丸生精细胞和精子遗传损伤的初步研究 ...