Immunophenotyping data were used to classify cases as T cell (CD7+ plus CD5+ or CD2+), B cell (sIgμ+), pre-B (cIgμ+), or early pre-B (CD19+, CD22±, HLA-DR+, CD7-, CD5-, cIgμ-, sIgμ-, and CD10). Cytogenetic and DNA flow cytometric studies. Immediately after ...
In this study we show that uncommitted human CD4+ CD45RA+ RO- CD25- CD71- HLA-DR- T cells can be primed for a Th2 phenotype before they encounter TCR signa... V Brinkmann,B Kinzel,C Kristofic - 《Journal of Immunology》 被引量: 56发表: 1996年 Viruses in Type 1 Diabetes: Brief ...
CD45RA−CCR7−Treg subset suppress CD8+T-cell functions via IL-10 secretion and cell–cell contact mechanisms. (a) Representative surface staining and statistics analysis of the expression of HLA-DR on CD45RA−CCR7−(blue), CD45RA−CCR7+(red) or CD45RA+CCR7−(green) Treg subsets...
Since CMV-specific T-cell response embodies a heterogeneous mixture of distinct and mainly CD8+ T-cell phenotypes with different functions [37,46], we aimed to comprehensively investigate the effect of TN depletion on the phenotype and functionality of the resulting CMV-specific memory T-cell ...