CD45RA depletion in HLA- mismatched allogeneic hematopoietic stem cell transplantation for primary combined immunodeficiency: a preliminary study[J].J Allergy Clin Immunol,2015, 135(5): 1303-1309.Touzot F, Neven B, Dal-Cortivo L, Gabrion A, Moshous D, Cros G, Chomton M, Luby JM, Terni...
作者: JJ Orozco,T Bäck,A Kenoyer,ER Balkin,DK Hamlin,DS Wilbur,DR Fisher,SL Frayo,MD Hylarides,DJ Green 展开 摘要: Despite aggressive chemotherapy combined with hematopoietic stem cell transplantation (HSCT), many patients with acute myeloid leukemia (AML) relapse. Radioimmunotherapy (RIT) us...
CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses ...
Altered HLA-DR expression and apoptosis have been described to reflect a state of immunological dysfunction in uremia. Here, we performed a cross-sectional... MD Cal,DN Cruz,V Corradi,... - 《Blood Purification》 被引量: 62发表: 2008年 Monocyte cell-surface CD14 expression and soluble CD14...
未治疗HIV/AIDS患者CD4CD25Foxp3CD45RO记忆性调节性T细胞百分率与CD4T细胞显著负相关(【:一0.690,P<0.001),与病毒载量明显正相关(r=0.401,P:0.002),与CD4HLA.DR、CD8HLA.DR、CD8CD38细胞显著正相关(P<0.05),与CD4CD95、CD8CD95T细胞水平显著正相关(P<0.05)。结论:HIV感染者CIMCD25Foxp3CIM5RO记忆性调节性...
Parkinson's disease and immunological abnormalities: increase of HLA-DR expression on monocytes in cerebrospinal fluid and of CD45RO+ T cells in peripheral... The etiology of Parkinson's disease is mainly unknown. Immune abnormalities have been described, but the cause of such abnormalities has no...
CD45RA−CCR7−Treg subset suppress CD8+T-cell functions via IL-10 secretion and cell–cell contact mechanisms. (a) Representative surface staining and statistics analysis of the expression of HLA-DR on CD45RA−CCR7−(blue), CD45RA−CCR7+(red) or CD45RA+CCR7−(green) Treg subsets...
Martin R, Howell MD, Jaraquemada D, Flerlage M, Richert J, Brostoff S, Long EO, McFarlin DE, McFarland HF: A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR type associated with multiple sclerosis. J Exp Med 173:19–24, 1991 3. Ben-...
McGeer PL, Itagaki S, Boyes BE, McGeer EG: Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology. 1988, 38 (8): 1285-91. PubMed CAS Google Scholar McGeer EG, McGeer PL: The role of the immune system in neurode...
Interestingly, both in vitro expanded cell populations lacked expression of HLA-DR (previously detected on the CD13high CD105+ CD45– cells from all samples studied ex vivo), suggesting the ex vivo identified CD13high CD105+ CD45– cells in fact fulfill all minimal criteria for the ...