•CD44: 记忆T细胞的标记物,在抗原刺激后上调•CD62L (L-selectin): 淋巴结归巢受体,在效应和效应记忆T细胞上下调 再看图(图源:https://secondgendesi.com/t-cell-tidbits/) 通过CD44和CD62L,将CD4+T细胞主要分为三群: •初始T细胞...
•CD44: 记忆T细胞的标记物,在抗原刺激后上调•CD62L (L-selectin): 淋巴结归巢受体,在效应和效应记忆T细胞上下调 再看图,可能有点糊,第一个小图的圈CD4+T,第二个小图横坐标CD62L,纵坐标CD44(图源:https://www.biolegend.com/fr-ch/products/mouse-naive-memory-t-cell-id-panel-9757) 通过CD44和CD...
美天旎（Milernyi Biotec）公司的磁珠分选试剂盒中有NaïveCD4+ T Cell Isolation Kit, mouse采用CD45...
NK Cells Regulate CD62L − CD44 − T Cell Subset in the Development of Pathogenic T Cells in a Murine Model of Colitisgastric cancermolecular biomarkerprognostic factorGLOIdoi:10.1016/S0016-5085(11)62016-7Osamu YamajiTeruji TotsukaTakashi Nagaishi...
使用 CD3ε 或 TCR-β 作为选择标记分析 CD4 T 细胞,可以避免将弱表达CD4的髓系细胞圈进来,这至关重要。某些组织中可能需要额外的标记来区分常规 CD4 T 细胞与其他非常规 T 细胞亚群,例如肝脏中的 CD4 + NKT 细胞。 CD4+ 初始 T (Tn) 细胞表型是 C...
T EM:效应记忆T细胞(Effector memory T Cell):CD44+CD62L- T CM:中枢记忆T细胞(Central memory T Cell):CD44+CD62L+ T pm:外周记忆T细胞(Peripheral Memory T Cell) T RM:组织驻留记忆T细胞(Tissue Resident Memory) TRM也是一个异质性群体,除了CD69,CD103,CXCR6等共有标志物之外,根据其他标志物,可以将TR...
The Mouse CD4+/CD62L+/CD44lowNaïve T Cell Enrichment Column Kit contains the following components to isolate mouse CD4+/CD62L+/CD44lownaïve T cells. Mouse CD4+/CD62L+/CD44lowNaïve T Cell Subset Columns Monoclonal Antibody Cocktail ...
老年人的线粒体功能和1-碳代谢低于年轻人CD4+ T细胞,提示T细胞衰老与1-碳代谢失活之间可能存在联系。下文作者2发现老年小鼠中,P4亚群(P1至P4亚群由CD44和CD62L阳性定义:CD44low/CD62Lhigh (naive; P1), CD44high/CD62Lhigh (central memory; P2), CD44high/CD62Llow (effector/memory; P3), and CD44...
We found inefficient generation of CD44 low CD62L low CD8 T cell subset (P4) in draining lymph nodes of tumor-bearing aged mice. In vitro stimulation of naive CD8 T cells first generated P4 cells, followed by effector/memory T cells. The P4 cells contained a unique set of genes related...
Chronological changes of CD4(+) and CD8(+) T cell subsets in the experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis. Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS). The etiology of MS remains unclear, but T cells specific for...