调节性T细胞（regulatory T cells，Treg），是一类具有显著免疫抑制作用的T细胞亚群。Treg作为免疫系统的调...
NK Cells Regulate CD62L − CD44 − T Cell Subset in the Development of Pathogenic T Cells in a Murine Model of Colitisgastric cancermolecular biomarkerprognostic factorGLOIdoi:10.1016/S0016-5085(11)62016-7Osamu YamajiTeruji TotsukaTakashi Nagaishi...
在CD45.2+的免疫细胞中,还可通过CD19和TCRβ分为CD19+的B细胞和TCRβ+的T细胞,在CD19-TCRβ-区域中,存在一类CD49b+NKp46+的NK细胞。T细胞可进一步根据CD4和CD8 分为辅助T和细胞毒T,这两个亚群根据CD44和CD62L区分出初始、记忆、效应三个功能状态。 简单明了的方案,值得正在做小鼠模型的你收藏。 参考文献...
起始样本为脾脏单细胞悬液,分选后初始CD4+T细胞(CD4 + CD44low CD62L高)纯度通常在91.7%-96.7%。 在上述样本中,分选前后初始CD4+T细胞的纯度分别是17.9%和92.4%。 组成成分: ▪EasySep™小鼠初始CD4+ T细胞预富集抗体混合物,0.5mL ▪EasySep™链霉亲和素包被磁珠™50001,1mL ...
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. IL-17-producing CD8+ T (Tcl7) cells are detectible in multiple sclerosis (MS) lesions; however, their contri-bution to the disease is unknown. To identify ... Huber,Magdalena - 《Journal of Clinical Investi...
Why Isolate CD4+/CD62L+/CD44lowNaïve T cells? Mouse CD4+T cells develop in the thymus and are released as naïve T cells that also express CD62L and low levels of CD44. These cells differentiate into subsets of specialized effector T lymphocytes in response to distinct environmental ...
Resveratrol Ameliorates Atherosclerosis Induced by High-fat Diet and LPS in ApoE-/- Mice and Inhibits the Activation of CD4+ T Cells Besides, RES decreased the number of CD4+ T cells in peripheral blood, decreased the expression of CD25 and CD44, but not affected the expression of L-selectin...
3.查到小鼠的是效应细胞CD44+CD62L-,记忆细胞CD44+CD62L+,初始细胞CD44-CD62L+. 现在想知道大鼠的可以用小鼠的这几个标志吗?大鼠的,大家还有没有其他的推荐呢? tiger CD62L is a 74-95 kD glycoprotein,also known as L-selectin, LECAM-1, Ly-22 and MEL-14.It is a member of the selectin fa...
【关键词】溃疡性结肠炎;清肠栓;葡聚糖硫酸钠;CD44;CD62L;T淋巴细胞;小鼠 【中图分类号】 R285.5 【文献标志码】 A 【文章编号】 1007—1334(2014)05—0104—05 Efectof“QingchangSuppository”onexpressionofCD44andCD62LinsplenicCD4 T—cellsin micewithcolitisinducedbydextransulfatesodium WANGLi—Juan,LIU...
T EM:效应记忆T细胞(Effector memory T Cell):CD44+CD62L- T CM:中枢记忆T细胞(Central memory T Cell):CD44+CD62L+ T pm:外周记忆T细胞(Peripheral Memory T Cell) T RM:组织驻留记忆T细胞(Tissue Resident Memory) TRM也是一个异质性群体,除了CD69,CD103,CXCR6等共有标志物之外,根据其他标志物,可以将TR...