Osum KC, Jenkins MK. Toward a general model of CD4+ T cell subset specification and memory cell formation. Immunity. 2023;56(3):475-484. doi:10.1016/j.immuni.2023.02.010 Oh DY, Fong L. Cytotoxic CD4+ T cells in cancer: Expanding the immune effector toolbox. Immunity. 2021;54(12):27...
a cd4+ t-cell subset inhibits antigen-specific t-cell responses and prevents colitis. nature . 389(6652):737–42. [3]park h., et al., (2005) distinct lineage of cd4 t cells regulates tissue inflammation by producing interleukin 17 nat immunol , 6 (...
Osum KC, Jenkins MK. Toward a general model of CD4+ T cell subset specification and memory cell formation. Immunity. 2023;56(3):475-484. doi:10.1016/j.immuni.2023.02.010 Oh DY, Fong L. Cytotoxic CD4+ T cells in cancer: Expanding the immune effector toolbox. Immunity. 2021;54(12):27...
初始CD4 T细胞,在TCR通路和细胞因子(主要是IL-6、TGF-β)的刺激下开始向Th17亚群分化,随后IL-21(主要由旁分泌和自分泌途径产生)促进Th17细胞亚群增殖,IL-23则维持Th17亚群的活性并促使其分泌IL17,从而产生促炎症反应。 当然,CD4 T细胞亚群众多,我们只介绍了三种常见的Th细胞亚群。Treg细胞,虽然也属于CD4 T细胞,...
4.Zander R, Schauder D, Xin G, Nguyen C, Wu XP, Zajac A, Cui WG: CD4(+) T Cell Help Is Required for the Formation of a Cytolytic CD8(+) T Cell Subset that Protects against Chronic Infection and Cancer. Immunity 2019, 51(6):1028-+. ...
4.Zander R, Schauder D, Xin G, Nguyen C, Wu XP, Zajac A, Cui WG: CD4(+) T Cell Help Is Required for the Formation of a Cytolytic CD8(+) T Cell Subset that Protects against Chronic Infection and Cancer. Immunity 2019, 51(6):1028-+. ...
[1] Takeuchi A , Saito T . CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function[J]. Frontiers in Immunology, 2017, 8:194. [2] Juno J A , David V B , Kent S J , et al. Cytotoxic CD4 T Cells—Friend or Foe during Viral Infection?[J]. Frontiers in...
关键词结核,肺;表位;T淋巴细胞亚群;记忆细胞AnalysisofCD4+memoryTcellsubsetsinpatientswithpulmonarytuberculosisCAOZhi-hong*,CHENGXiao-xing,WANGXin-jing,NIUHan-jie,DONGMei,TONGAi-hua*LaboratoryofTuberculosis,ChinesePLAGeneralHospital2ndClinicalDivision,Beijing100091,ChinaCorrespondingauthor:CHENGXiao-xingE-mail:xc...
TakeuchiA and Saito T (2017) CD4 CTL, a Cytotoxic Subset of CD4+ T Cells, Their Differentiation and Function. Front. Immunol. 8:194. doi: 10.3389/fimmu.2017.00194 来源: 闲谈 Immunology 2022-10-25
Recent findings, however, beg re-evaluation of the direct role of Th2 cells in the induction or maintenance of tolerance, whereas evidence for the role of a distinct subset of regulatory T cells producing TGF-β to suppress cell-mediated immunopathology is compelling. 展开 关键词: BRAIN ...