6. Madeline A. Lancaster and Juergen A. Knoblich. Generation of Cerebral Organoids from Human Pluripotent Stem Cells. Nature Protocols, 2014. https://doi.org/10.1038/nprot.2014.158.7. Sebastian, R., et al. Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-sp...
造血干细胞(Hematopoietic stem cells,HSCs)具有形成机体所有血细胞和免疫细胞谱系的能力,是维持机体血液和免疫稳态的关键细胞,因此HSCs移植(HSCT)长期以来一直是诸如急性髓系白血病、重度再生障碍性贫血等血液系统疾病的常规治疗方法。目前在骨髓、动员...
Often overlooked stem cells hold hidden powers for blood disease treatments https://medicalxpress.com/news/2024-03-overlooked-stem-cells-hidden-powers.html
These methods use CD34- stem cells, have the advantages that the very big treatment for being them and not needing progress marrow removing patient. Whether CD34- stem cells can be by genetic modification for instant method, the treatment depending on illness.Huss Ralf...
STEM cellsDENTAL pulpBONE regenerationIMMUNOFLUORESCENCEX-ray diffractionTRANSPLANTATION of organs, tissues, etc.Objectives: The aim of this study was to select and provide enough stem cells for quick transplantation in bone engineering procedures, avoiding any in vitro expansion ...
CD34是一种高度糖基化的细胞表面抗原,优先并广泛地表达于人类及其他哺乳动物造血干/祖细胞(hematopoietic stem and progenitor cells,HSPC)表面,属于唾液粘蛋白家族(Sialomucin)。 随着研究的深入,科研人员发现CD34也标记多种组织的常驻祖细胞,包括血液、基质/纤维/脂肪细胞祖细胞(FAPs)...
近日,中国医学科学院血液病医院(中国医学科学院血液学研究所)、北京协和医学院和中国科学技术大学附属第一医院研究团队联合在《白血病》(Leukemia)杂志发表题为“Are haematopoietic stem cell transplants stem cell transplants, is there a threshold dose of CD34-positive cells and how many are needed for rapid...
25、etic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science, 1996, 273: 242-2455Jones RJ, Collector MI, Barber JP, et al. Characterization of mouse lymphohematopoietic stem cells lacking spleen colony-forming activity. Blood, 1996,88:487-491.6Morel F, Galy A, Chen ...
Recent data have suggested that human CD34- hematopoietic stem cells (HSCs) exist, challenging the concept that HSCs necessarily and exclusively express the CD34 antigen. In mice, quiescent HSCs have been shown to be mostly CD34-, but as a consequence of 5-fluorouracil treatment or cytokine stimu...