近日,中国医学科学院血液病医院(中国医学科学院血液学研究所)、北京协和医学院和中国科学技术大学附属第一医院研究团队联合在《Leukemia》发表题为“Are haematopoietic stem cell transplants stem cell transplants, is there a threshold dose of CD34-positive cells and how many are needed for rapid posttransplan...
Peripheral blood stem cellsTo evaluate CD34+ selection of peripheral blood stem cells (PBSC) as a graft for autologous transplantation. Eight relapsing follicular lymphoma (FL) patients were submitted to CD34+ autologous stem cell transplantation (ASCT). All patients received at least two front line...
CD34是造血干细胞移植(hematopoietic stem cell transplant, HSCT)的临床生物标志物,表达CD34的细胞是临床上造血干细胞移植中供体组织长期再生潜力的主要来源。CD34蛋白的表面表达通常随着细胞的成熟逐渐减弱,并在细胞成熟为终端效应体时消失。基于这种表达模式,CD34在HSCT中评价或选择移植供体组织方面具有核心作用。在过去的...
stem cells was performed on aCliniMACS device, observing GMP and achieving a median of98.5% purity. The patients received a median of 1.7 ? / 10 6 /kgCD34 ? cells and 2.5 ? / 10 3 /kg CD3 ? T lymphocytes.ResultsHemograms at days ? / 30, ? / 60 and ? / 90, respectively, sho...
CD34是造血干细胞移植(hematopoietic stem cell transplant, HSCT)的临床生物标志物,表达CD34的细胞是临床上造血干细胞移植中供体组织长期再生潜力的主要来源。CD34蛋白的表面表达通常随着细胞的成熟逐渐减弱,并在细胞成熟为终端效应体时消失。基于这种表达模式,CD34在HSCT中评价或选择移...
Over the past 3 years we have performed 10 haploidentical peripheral blood stem cell transplants in patients with incurable haematological malignancies and no prospect of a matched unrelated donor within an adequate time period. Conditioning consisted of ATG, TBI, thiotepa, cyclophosphamide and additiona...
Garnier A, Le Bourgeois A, Chevallier P, Béné MC. Impact on outcomes of mixed chimerism of bone marrow CD34+ sorted cells after matched or haploidentical allogeneic stem cell transplantation for myeloid malignancies. Bone Marrow Transpl...
Alici E, Bjorkstrand B, Treschow A, et al: Long-term follow-up of gene-marked CD34+ cells after autologous stem cell trans- plantation for multiple myeloma. Cancer Gene Ther 14: 227-232, 2007.Alici E, et al. Long‐term follow‐up of gene‐marked CD34+ cells after autologous stem ...
Number of viable CD34+ cells reinfused predicts engraftment in autologous hematopoietic stem cell transplantation. Presents information on a study which examined the effects of reduced CD34+ cell viability due to cryopreservation on hematopoietic stem cell transplantati... Allan,S D.,Keeney,... - 《...
T cell alloreactivity induced by normal G-CSF-mobilized CD34+ blood cells Bone Marrow Transplant., 21 (1998), pp. 1183-1191 CrossrefView in ScopusGoogle Scholar 6 F Van Rhee, Y.-Z Jiang, F Vigue, et al. Human G-CSF-mobilized CD34-positive peripheral blood progenitor cells can stimulate...