In this study, activating and inhibitory receptor expressions and interleukin (IL)-22 levels of NK cells were investigated in RR-MS patients with or without IFN-beta therapy. Activating receptor expression and IL-22 levels of NK cells were increased in RR-MS patients under IFN-beta therapy. ...
对近些年的研究进行总结和整理,发现CD3和CD28的协同免疫性,通常是研究的一个关键点。其中将CD3单抗与CD28单抗联用可以促进一些免疫细胞的增殖,同时提高免疫细胞对肿瘤的杀伤能力。既兼具T淋巴细胞的抗肿瘤活性同时保留了NK细胞的非MHC限制性的对肿瘤细胞的杀伤作用 ...
NK and NK-like T cells play an essential role in linking innate and adaptive immunity through their ability to secrete IFN-γ. The exact trigger initiating production of IFN-γ is uncertain. Antigen-presenting cell (APC)-derived IL-12 is thought to be the classical IFN-γ-inducing cytokine ...
CD3AK(Anti-CD3 Antibody induced activated killer cells)是抗CD3单克隆抗体和IL-2共同激活的杀伤细胞,具有强体外增殖能力、高效细胞毒活性。是继LAK、TIL细胞后又一具有杀伤肿瘤作用的免疫活性细胞,与LAK细胞及TIL细胞相比较,CD3AK细胞具有扩增能力强、体外存活时间较长、细胞毒活性高、分泌淋巴因子的能力强和体内外...
Cell Type: NK and NKT Cells, T Cells, Treg cells, Th17 cells Preperation: The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of ...
The CD3- 16+ 56+ NK cell count independently predicts autologous blood stem cell mobilization.Antigens, CD3Killer Cells, NaturalCOUNTAutologousBloodHematopoietic Stem Cell Mobilization抗原, CD3杀伤细胞, 天然血液造血干细胞动员Better predictive factors for autologous blood stem cell mobilization (BSCM) are...
关键词: NK细胞 / 抗CD3单抗 / IL-2 / 过继免疫治疗 Abstract: Objective To study the expanding way of human cytotoxic CD3-CD56+ NK cells from peripheral blood mononuclear cells PBMC. Methods PBMCs were cultured in stem cell growth medium SCGM or RPMI 1640 supplemented with monoclonal anti-CD...
High IFN-gamma and TNF production by peripheral NK cells of Colombian patients with different clinical presentation of Plasmodium falciparum NK cells in the different patient groups./p pResults/p pThe total mean CD56sup+/sup/CD3sup- /supNK cell proportions in acute and severe malaria ... O ...
provided a simple and efficient way of expanding andenriching human NK cells for the adoptive immunotheraphy of tumor with NK cells.Key words:Natural killer cells;Anti -CD3 antibodies;Interleukin-2;Adoptive immunotheraphy摘 要:目的 探索从人 PBMC 中高效扩增细胞毒性 CD3 - CD56 + NK 细胞的方法...
NKp461+CD3+ cells: A novel nonconventional T cell subset in cattle exhibiting both NK cell and T Cell features NKp46+ CD3+ cells: a novel nonconventional T cell subset in cattle exhibiting both NK cell and T cell features. J Immunol. 2014;192(8):3868-80... Storset,K A.,Hope,......