CD19 expression in B cells is important for suppression of contact hypersensitivity. Watanabe R,Fujimoto M,Ishiura N,Kuwano Y,Nakashima H,Yazawa N,Okochi H,Sato S,Tedder TF,Tamaki K. American Journal of Pathology . 2007Watanabe R, Fujimoto M, Ishiura N, Kuwano Y, Nakashima H, Yazawa N...
SARS-CoV-2 infection alters the immune phenotype and function of B cells and reduces CD19 expression on B cells from recovered COVID-19 patients. Flow cytometry analysis of the frequencies of naive B cells (naive, CD19+IgD+CD27−), class-switched B cells (switched, CD19+IgD−CD27+)...
CD81 is crucial for the expression of CD19 on the plasma membrane in human B cells. It associates with cell-specific partners such as CD19 (and indirectly CD21) on B cells, whereas on T cells it associates with CD4 and CD8 [21]. On B cells, the protein serves as the anchor of ...
Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells. J Exp Med. 2008;205:409–21. Article CAS PubMed PubMed Central Google Scholar Anagnostou T, Riaz IB, Hashmi SK, Murad MH, Kenderian SS. Anti-CD19 chimeric...
Human B cells are lymphocytes that are characterized by the expression of CD19 on the cell surface. These cells are one of the main cell types involved in the humoral immune response. Upon activation, due to an encounter with an antigen, B cells will act as antigen presenting cells (APCs)...
in vivo B cell depletion Sawen, P., et al. (2016). “Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis.” Cell Rep 14(12): 2809-2818 Flow cytometry Becker, A. M., et al. (2015). “ADA...
in vivo B cell depletion Sawen, P., et al. (2016). “Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis.” Cell Rep 14(12): 2809-2818 Flow cytometry Becker, A. M., et al. (2015). “ADAM17 limits the expression of CSF1R on murine hematopoi...
Dynabeads CD19 Pan B are superparamagnetic beads covalently coupled with an anti-human CD19 antibody that enable easy isolation or depletion of human CD19+ B cells directly from whole blood, bone marrow, buffy coat, PBMC and tissue digests. ...
Furthermore, IL-21 co-expression improved the in vivo persistence of CAR-NK cells and significantly suppressed tumor growth in a xenograft Raji lymphoma murine model, leading to prolonged survival of CD19+ tumor-bearing mice. RNA sequencing revealed that CAR-21 NK cells have a distinct ...
(8;21). These cells consistently express the B-cell-specific transcription factor PAX5, and the B-cell-specific cell surface protein CD19. However, the functional consequences of PAX5 expression are unknown. To address this question, we studied the chromatin features of CD19, which is a ...