Subimerb C, Pinlaor S, Lulitanond V, Khuntikeo N, Okada S, McGrath MS, Wongkham S. Circulating cd14(+) cd16(+) monocyte levels predict tissue invasive character of cholangiocarcinoma. Clin Exp Immunol. 2010; 161 :471–479.Subimerb C, Pinlaor S, Lulita...
CD14++CD16− monocytes, frequently described as classical monocytes, dominate in the peripheral circulation, compared to ‘non-classical’ CD14+CD16++. More recent work has identified an additional intermediate monocyte subset: CD14++CD16+ monocytes numerically represent the smallest monocyte population...
In this regard, it has been observed that during TB infection, CD16 monocytes exhibit perturbation and are associated with disease severity. Monocyte subsets have also been shown to modulate their cytokine production under infectious and non-infectious conditions [14], [15]. A few other studies ...
human blood monocyte subsets; CD14; CD16; HLA-DR; liver failure Abstract Changes in monocytes and their subsets (CD14hi/CD16neg, CD14hi/CD16pos and CD14lo/CD16pos) have been described in several diseases. The combination of CD14, CD16 and HLA-DR has been suggested to discriminate monocyte...
The novel subset of CD14+/CD16+ blood monocytes is expanded in sepsis patients Staining with CD14 and CD16 monoclonal antibodies will identify two monocyte subpopulations in human blood: a major population of regular monocytes, which ... Fingerle GA,A Pforte,B Passlick,... - 《Blood》 被引...
Gene Ontology (GO) enrichment analysis suggests diverse immunologic functions, linking CD14++CD16+ monocytes to Ag processing and presentation (eg, CD74, HLA-DR, IFI30, CTSB), to inflammation and monocyte activation (eg, TGFB1, AIF1, PTPN6), and to angiogenesis (eg, TIE2, CD105). In ...
Peripheral blood mononuclear cells (PBMCs) of the study participants were isolated and processed to characterize the monocyte subsets based on CD14 and CD16 expression in flow cytometry. Monocyte intracellular cytokine expression (IL-10, IL-6, TNF-α and IL-1) was assessed after Lipopolysaccharide...
Monocytes are a heterogeneous group of leukocytes subdivided into distinct subsets: classical monocytes comprise over 80% of circulating monocytes, are highly positive for CD14 (CD14bright) and typically CD16-negative, while CD16-positive monocytes have been further subdivided into intermediate CD14bright...
S2d). These collective findings signify an overall escalation in monocyte-related gene programs and impaired T cell-mediated anti-tumor functions in the peripheral immune cells of non-responders before ICB therapy. Further examination is required to unveil the contribution of monocytes to the limited ...
The CD14(bright) CD16+ monocyte subset is expanded in rheumatoid arthritis and promotes expansion of the Th17 cell population. Arthritis Rheum. 2012;64(3):671-677.Rossol M, Kraus S, Pierer M, Baerwald C, Wagner U. The CD14(bright) CD16+ monocyte subset is expanded in rheumatoid arthritis...