Cell Type B Cells, Plasma Species Mouse Sample Source Bone Marrow, Lymph Node, Other, Spleen Selection Method Positive Application Cell Isolation Brand EasySep, RoboSep Area of Interest Immunology Data Figures Figure 1. Typical EasySep™ Mouse CD138 Positive Cell Isolation Pr...
CD138 + Plasma Cell Isolation Kit mouseKit, Isolation
(B-cell, 49; T-cell, 8; Hodgkin lymphoma, 19), 1 Langerhans cell histiocytosis, and 14 nonneoplastic lymph nodes revealed CD138 reactivity only for nonneoplastic plasma cells, the neoplastic cells of 2 large B-cell lymphomas (immunoblastic type, plasmacytoid features), and the clonal plasma...
-1 participates in cell proliferation, cellmigration, and cell matrix adhesion via interaction with collagen, fibronectin, and other solublemolecules (such as FGF-basic). It is expressed on normal and malignant plasma cells, pre-Bcells, mesenchymal cells, epithelial cells, and endothelial cells....
产品介绍Product Description CD138, also known as syndecan-1, is a type I integral membrane protein belonging to the syndecan protein family which carries three to five heparan sulfate and chondroitin sulfate chains. CD138 is highly expressed on plasma cells and pre–B cells but not on mature ...
CD138 is highly expressed on plasma cells and pre–B cells but not on mature peripheral B cells. It is also expressed on fibroblasts and epithelial cells. The expression of CD138 can be regulated by several cytokines and factors, e.g., thrombin, which is reported to increase the synthesis...
Staining of in vitro generated human plasma cells. Enriched and stimulated B-cells were stained with CD19 Monoclonal Antibody, PE (Product # 12-0199-42), CD38 Monoclonal Antibody, FITC (Product # 11-0389-42) and Mouse IgG1 kappa Isotype Control, PE-eFluor610 (Produc...
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[1] In lymphoid tissues, CD138 is expressed in the late stages of B-cell differentiation with progression towards plasma cells.[1][2] Anti-CD138 is a good marker to selectively identify plasma cells, benign or malignant, in lymphoid tissues CD138 is also expressed in a variety of ...
It is a heparan sulfate proteoglycan expressed on the surface of, and actively shed by, myeloma cells. Altered syndecan-1 expression has been detected in several different tumor types. CD138 was regarded as a useful marker for labeling normal and neoplastic plasma cells and plasmacytoid lymphomas....