三、树突状细胞 (DC) 临床意义:树突状细胞(DC)的主要功能是吸收抗原,进行加工,并向T淋巴细胞呈递。DC细胞具有诱导初发免疫反应的独特功能,例如,可以活化处女T细胞(Naive T cell)。DC细胞存在于外周淋巴组织中,已在血液和非淋巴器官中发现了不同类型的DC细胞,并被认为是淋巴组织中细胞的前体。CD123+ DC和CD11c+...
CD127 是白介素 -7 受体 α链,它主要在淋巴前体细胞(pre-L )、 B 祖细胞( pro-B )、 T 细胞、胸腺细胞、髓样细胞及单核细胞表达,也可在持续表达病毒特异性 CD8 + T 细胞表面表达,在 T 淋巴细胞发育过程中,胸腺细胞的分化依赖于 IL-7 的表达; IL-7 是外周成熟 T 细胞稳态维持的重要调节因子;同时...
In an attempt to identify markers that are sensitive and specific for human T-regs, we analyzed the expression of fourteen intracellular and cell surface markers on human CD4 + cells. Many markers were partially selective for CD25 hi T-regs, but consistent and specific discrimination of ...
【关键词】调节性T细胞HIV感染高效抗逆转录病毒治疗 PeripheralCD4 + /CD25 hi /CD127 low TregcelllevelsinHIVpatientsafterantiviraltherapyanditssignificance China 【Abstract】ObjectiveToinvestigateperipheralbloodCD4 + /CD25 hi /CD127 low RegulatoryTcell(Treg)levelsinHIVpatients afterantiviraltherapyanditsclinical...
产品类型:T细胞分选 规格:100tests,50 tests 712810,712805 我要询价 添加 STEMCELL Technologies EasySep™ Human Naïve CD8+ T Cell Isolation Kit II/EasySep™人初始 CD8+ T细胞分选试剂盒 II 产品类型:T细胞分选 规格:用于标记 1 x 10e9细胞,用于标记 1 x 10e9细胞 17968,17968RF 我要询价 添加Rever...
J Immunol ,2000 ;165 (3) :1395-1402 【4】 Xiao T,Kagami S ,Saeki H et al .Both IL24 and IL213 inhibit the TNF2al2pha and IFN2gamma enhanced MDC production in a human keratinocytecell line ,HaCaT cells[J] . J Dermatol Sci ,2003 ;31 (2) :111-117 【5】Hermann C ,Assmus B...
Schlom J., Sabzevari H., Inhibition of CD4+25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood. 2005.105:2862–2868 【10】Attia P., Maker AV., Haworth LR., Rogers-Freezer L. & Rosenberg SA., Inability of a fusion protein of IL-2 and...
(p﹤0.05). SAA compared to patients with CAA, SAA was lower than CAA(p﹤0.05). Aplastic anemia in children with CD4+CD25+CD127lowT cell percentage and expression of TGF-β1level were no significant correlation.Conclusion:The low percentage of regulatory T cells and expression of TGF-β1...
CD4 + CD25 + CD127 - 调节性T细胞在胃癌不同TNM分期中的表达 康文喜樊静河北省秦皇岛市肿瘤医院邮编:066001 摘要目的:探讨CD4 + CD25 + CD127 - 调节性T细胞(Tregs)在胃癌患者不同TNM分期外 周血中的表达。方法:采用流式细胞仪检测2...
HIV-specific TGF-β-positive CD4+ T cells do not express regulatory surface markers and are regulated by CTLA-4 CD4(+) T cell dysfunction in HIV-1 infection is associated with increased CTLA-4 and TGF-beta expression. In this study we described a population of TGF-be... M Elrefaei,CM...