Administration of DT at day 1 in DTR mice resulted in macrophage ablation at day 2–3 after injury with an increase in macrophages at day 4. Thus, the early recruitment of proinflammatory macrophages was critical for muscle regeneration; further studies are needed to define markers present on ...
Diphtheria toxin injection into CD11b DTR transgenic mice.MyungGyu, KimSun, Chul KimYoon, Sook KoHee, Young LeeSangKyung, JoWonyong, Cho