PMA诱导人单核细胞白血病细胞株THP-1细胞表面标志物CD14和CD11b的表达
方法 首先用 PMA梯度剂量(0,25,50,100,200,400ng/ml)作用于 THP 1细胞 24h,通过 CCK 8法检测细胞活力,再分别采用 0,10,50ng/mlPMA体外刺激 THP 1细胞 24h、48h,流式细胞术检测细胞表面标志物 CD11b、CD14。 结果 梯度 PMA剂量(0-100ng/ml)对细胞活力没有影响(P>005)。10ng/ml、50ng/mlPMA处理...
In conclusion, the C3-C3b-iC3b axis is activated already in the early vasculitis lesion leading to progressive accumulation of CD11b and CD14 cells.Rahkola, DinaLipits, TiinaSiiskonen, HannaNaukkarinen, AnitaHarvima, Ilkka T.Analytical Cellular Pathology: Cellular Oncology...
a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and...
a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and...
a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and...
andapoptosis. The particular integrin CD11b is known as a pro-inflammatory molecule given its ability to promote phagocyte cytotoxic functions while enhancing several effector molecules such as FcGR,uPAR, andCD14(1). In macrophages, CpG-DNA stimulateslysosomaldegradation and vacuolar acidification, subseq...
Conventional/Classical Dendritic Cells Granulocyte Markers Inflammatory/Monocyte-derived Dendritic Cells Integrins and Associated Molecules Isolation, Culture, and Identification of Natural Killer Cells Langerhans and Dermal Dendritic Cells Microglia Activation ...
(CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial ...