We hypothesized that these cells could play a role in taste bud immunity as glial cells do in the brain. We purified type I TBC, expressing F4/80, a specific marker of macrophages, from mouse fungiform taste papillae. The purified cells also express CD11b, CD11c, and CD64,...
isolated from homogenized whole mouse brains by magnetic bead-positive selection for CD11b to analyze expression of CASP11 by immunoblot. The non-microglia (CD11b −) fraction was also collected and contains all cell types other than microglia, such as neurons, endothelial cells, astrocytes, ...
H&E staining (F) and Lm analyses (G) were assessed as described earlier, and the number of lung IL-17A+γδ T cells (H) and lung neutrophils (CD11b+Ly6G+) (I) was determined by flow cytometry. Each symbol represents an individual mouse, and horizontal lines indicate the mean. Data ...
以流式細胞儀分析健康犬及腫瘤患犬白血球CD45,CD11b及NSA之表現及荷犬乳腺癌細胞株NOD/SCID小鼠之MDSCs改變Flow cytometric analysis of CD45, CD11b and NSA express... Results revealed that there is a significant decrease in the percentage of large and high granularity cells with medium or increased...
[65]. The specific mechanism of pre-metastatic niche is not yet clear. Before metastatic niche is formed in the liver, tumor cells need to break through the liver’s self-protection system, and prioritize inflammatory microenvironment, making tumor cells more prone to spread and invade. ...
express the encoding proteins in vivo for inducing specific antibodies. Alternatively, lymphocytes may be immunized in vitro. Lymphocytes then are fused with myeloma cells using a suitable fusing agent, such as polyethylene glycol, to form a hybridoma cell (Goding,Monoclonal Antibodies: Principles and...
X-axis: percentage of adherent cells Y-axis: antibody concentration —♦—: F1=Fab fragments of the antibody CD28.1 —▪—: F2=Fab fragments of the antibody CD28.2 —▴—: F3=Fab fragments of the antibody CD28.3 —x—: F5=Fab fragments of the antibody CD28.5 —*—: F6=Fab fragm...
Here we describe-a novel population of CD11b+F4/80+CD11c- antigen-presenting cells, localized within the intestinal lamina propia, that potently suppresses immune responses. Such cells spontaneously secrete robust levels of IL-10, and express an anti-inflammatory gene expression signature, but ...
A unique subpopulation of circulating CD11b+ myeloid and CD11b+/CD115+ monocytes that express the stretch activated cation channel Piezo‐1, which is enriched prominently in the clot‐like hydrogel, is identified. These findings offer evidence for a mechanobiology paradigm in angiogenesis involving ...
B16 tumors, and was imposed upon the tumor cells by CD11b + cells within the local brain tumor microenvironment. Combining T-cell costimulation with systemic VSV-cDNA treatment, long-term cures of mice with established i.c. tumors were achieved in about 75% of mice. Our data show that ...